Product Information
Name:N-Desmethyl Clozapine
Controlled Product
Synonyms:
- Clozapine Imp. C (EP)
- 8-Chloro-11-(piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine
- Desmethylclozapine
- Norclozapine,5H-Dibenzo[b,e][1,4]diazepine
- 8-chloro-11-(1-piperazinyl)-
- 8-Chloro-11-(1-piperazinyl)-5H-dibenzo[b,e][1,4]diazepine
- ACP 104
- Demethylclozapine
- N-Demethylclozapine
- N-Desmethylclozapine
- Clozapine-desmethyl
Brand:TRC
Description:
Applications N-Desmethyl Clozapine is a metabolite of Clozapine (C587500). N-Desmethyl Clozapine is a potent, allosteric agonist at human M1 receptors and is able to potentiate hippocampal NMDA receptor currents through M1 receptor activation.
References Sur, C., et al.: Proc. Nat. Acad. Sci. U. S. A., 100, 13674 (2003); Kuoppamaki, M. et al.: Eur. J. Pharm. Mol. Pharm. Sect., 245, 179 (1993); Olessen, O.V., et al.: J. Chromatog., 622, 39 (1993); Pirmohamed, M., et al.: J. Pharmacol. Exp. Ther., 272, 984 (1995)
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:312.8
Formula:C17H17ClN4
Color/Form:Neat
InChI:InChI=1S/C17H17ClN4/c18-12-5-6-15-16(11-12)21-17(22-9-7-19-8-10-22)13-3-1-2-4-14(13)20-15/h1-6,11,19-20H,7-10H2
InChI key:InChIKey=JNNOSTQEZICQQP-UHFFFAOYSA-N
SMILES:Clc1ccc2c(c1)N=C(N1CCNCC1)c1ccccc1N2
Technical inquiry about: N-Desmethyl Clozapine
Please use instead the cart to request a quotation or an order
If you want to request a quotation or place an order, please add the desired products to your cart and manage the request from there. It is faster, cheaper, and you will be able to benefit from the available discounts and other advantages.