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N-Desmethyl Imatinib

CAS:

Ref. TR-D292045

5mg
436.00€
10mg
805.00€
50mg
2,408.00€
N-Desmethyl Imatinib
TRC

    Product Information

    Name:N-Desmethyl Imatinib
    Controlled Product
    Synonyms:
    • N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]-4-(1-piperazinylmethyl)-benzamide
    • N-Desmethylimatinib
    • N-[4-Methyl-3-[4-(pyridin-3-yl)pyrimidin-2-ylamino]phenyl]-4-[(piperazin-1-yl)methyl]benzamide
    • N-[4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]-4-(1-piperazinylmethyl)benzamide
    • Norimatinib
    • STI 509-00
    • Imatinib Imp. C (EP)
    Brand:TRC
    Description:Impurity Imatinib EP Impurity CApplications N-Desmethyl Imatinib (Imatinib EP Impurity C) is a metabolite of Gleevec, a tyrosine kinase inhibitor which is highly specific for BCR-ABL, the enzyme associated with chronic myelogenous leukemia (CML) and certain forms of acute lymphoblastic leukemia (ALL). It is a COVID19-related research product.References Schindler, T., et al.: Science, 289, 1938 (2000), Drucker, B.J., et al.: N. Engl. J. Med., 344, 1031 (2001),
    Notice:Our products are intended for lab use only. For any other use, please contact us.

    Chemical properties

    Molecular weight:479.58
    Formula:C28H29N7O
    Color/Form:Neat
    InChI:InChI=1S/C28H29N7O/c1-20-4-9-24(17-26(20)34-28-31-12-10-25(33-28)23-3-2-11-30-18-23)32-27(36)22-7-5-21(6-8-22)19-35-15-13-29-14-16-35/h2-12,17-18,29H,13-16,19H2,1H3,(H,32,36)(H,31,33,34)
    InChI key:InChIKey=BQQYXPHRXIZMDM-UHFFFAOYSA-N
    SMILES:Cc1ccc(NC(=O)c2ccc(CN3CCNCC3)cc2)cc1Nc1nccc(-c2cccnc2)n1

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