Product Information
Name:N-Desmethyl Imatinib
Controlled Product
Synonyms:
- N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]-4-(1-piperazinylmethyl)-benzamide
- N-Desmethylimatinib
- N-[4-Methyl-3-[4-(pyridin-3-yl)pyrimidin-2-ylamino]phenyl]-4-[(piperazin-1-yl)methyl]benzamide
- N-[4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]-4-(1-piperazinylmethyl)benzamide
- Norimatinib
- STI 509-00
- Imatinib Imp. C (EP)
Brand:TRC
Description:
Impurity Imatinib EP Impurity C
Applications N-Desmethyl Imatinib (Imatinib EP Impurity C) is a metabolite of Gleevec, a tyrosine kinase inhibitor which is highly specific for BCR-ABL, the enzyme associated with chronic myelogenous leukemia (CML) and certain forms of acute lymphoblastic leukemia (ALL). It is a COVID19-related research product.
References Schindler, T., et al.: Science, 289, 1938 (2000), Drucker, B.J., et al.: N. Engl. J. Med., 344, 1031 (2001),
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:479.58
Formula:C28H29N7O
Color/Form:Neat
InChI:InChI=1S/C28H29N7O/c1-20-4-9-24(17-26(20)34-28-31-12-10-25(33-28)23-3-2-11-30-18-23)32-27(36)22-7-5-21(6-8-22)19-35-15-13-29-14-16-35/h2-12,17-18,29H,13-16,19H2,1H3,(H,32,36)(H,31,33,34)
InChI key:InChIKey=BQQYXPHRXIZMDM-UHFFFAOYSA-N
SMILES:Cc1ccc(NC(=O)c2ccc(CN3CCNCC3)cc2)cc1Nc1nccc(-c2cccnc2)n1
Technical inquiry about: N-Desmethyl Imatinib
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