2',7'-Dichlorodihydrofluorescein Diacetate

CAS: 4091-99-0

Ref. TR-D434215

Product Information

• Name: 2',7'-Dichlorodihydrofluorescein Diacetate
• Synonyms: 2-[3,6-Bis(acetyloxy)-2,7-dichloro-9H-xanthen-9-yl]benzoic Acid, o-(2,7-Dichloro-3,6-dihydroxyxanthen-9-yl)benzoic Acid Diacetate, DCFH, H2DCFDA
• Brand: TRC

Description

Stability Light Sensitive
Applications 2',7'-Dichlorodihydrofluorescein as a cell-permeable non-fluorescent probe. It is de-esterified intracellularly and turns to highly fluorescent 2′,7′-dichlorofluorescein upon oxidation.
References Lebel, C., et al.: Chem. Res. Toxicol., 5, 227 (1992), Kjaer, M., et al.: Lipids, 43, 813 (2008), Baron, C., et al.: J. Agric. Food Chem., 57, 4185 (2009),

Chemical properties

• Molecular weight: 487.29
• Formula: C₂₄H₁₆Cl₂O₇
• Color/Form: Neat
• InChI: InChI=1S/C24H16Cl2O7/c1-11(27)31-21-9-19-15(7-17(21)25)23(13-5-3-4-6-14(13)24(29)30)16-8-18(26)22(32-12(2)28)10-20(16)33-19/h3-10,23H,1-2H3,(H,29,30)
• InChI key: InChIKey=PXEZTIWVRVSYOK-UHFFFAOYSA-N
• SMILES: CC(=O)Oc1cc2c(cc1Cl)C(c1ccccc1C(=O)O)c1cc(Cl)c(OC(C)=O)cc1O2