Product Information
Name:Epiberberine Chloride
Synonyms:
- 7,8,13,13a-Tetradehydro-2,3-dimethoxy-9,10-(methylenedioxy)berbinium Chloride
Brand:TRC
Description:Applications Epiberberine Chloride, is a natural bioactive alkaloid, an isomer of Berberine (B318150), an isoqinoline alkaloid shown to have a chemopreventive property against colon tumor formation by inhibiting the enzyme cyclooxygenase-2 (cox-2) which is abundantly expressed in colon cancer cells.References Zhang, X. et al.: Cancer Res., 70, 9895 (2010); Lin, H.L. et al.: Cancer 85, 1937(1999); Schumacher, M.A. et al.: Science, 294, 2158 (2001); Fukuda, K. et al.: J. Ethno., 66, 227(1999); Liu, X. et al.: J. Pharm. Biomed. Anal., 98, 463 (2014);
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:371.81
Formula:C20H18NO4·Cl
Color/Form:Neat
InChI:InChI=1S/C20H18NO4.ClH/c1-22-18-8-13-5-6-21-10-15-12(3-4-17-20(15)25-11-24-17)7-16(21)14(13)9-19(18)23-2;/h3-4,7-10H,5-6,11H2,1-2H3;1H/q+1;/p-1
InChI key:InChIKey=ZGJJVEJAMGFABG-UHFFFAOYSA-N
SMILES:O=C(O)c1ccnc(-c2csc(Nc3cccc(F)c3)n2)c1
Technical inquiry about: Epiberberine Chloride
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