Fosamprenavir Calcium Salt

CAS: 226700-81-8

Ref. TR-F727250

Product Information

• Name: Fosamprenavir Calcium Salt
• Synonyms: Carbamic acid, N-[(1S,2R)-3-[[(4-aminophenyl)sulfonyl](2-methylpropyl)amino]-1-(phenylmethyl)-2-(phosphonooxy)propyl]-, (3S)-tetrahydro-3-furanyl ester, calcium salt (1:1), Carbamic acid, [(1S,2R)-3-[[(4-aminophenyl)sulfonyl](2-methylpropyl)amino]-1-(phenylmethyl)-2-(phosphonooxy)propyl]-, C-[(3S)-tetrahydro-3-furanyl] ester, calcium salt (1:1) (9CI), Fosamprenavir calcium, GW 433908G, Lexiva, GW 433908G
• Brand: TRC
• Description: Applications HIV protease inhibitor; water soluble prodrug of amprenavir.References Falcoz, C., et al.: J. Clin. Pharmacol., 42, 887 92002), Chapman, T.M., et al.: Drugs, 64, 2101 (2004)

Chemical properties

• Molecular weight: 623.67
• Formula: C₂₅H₃₄N₃O₉PS·Ca
• Color/Form: White To Off-White
• InChI: InChI=1S/C25H36N3O9PS.Ca/c1-18(2)15-28(39(33,34)22-10-8-20(26)9-11-22)16-24(37-38(30,31)32)23(14-19-6-4-3-5-7-19)27-25(29)36-21-12-13-35-17-21;/h3-11,18,21,23-24H,12-17,26H2,1-2H3,(H,27,29)(H2,30,31,32);/q;+2/p-2/t21-,23-,24+;/m0./s1
• SMILES: CC(C)CN(C[C@@H](OP(=O)([O-])[O-])[C@H](Cc1ccccc1)NC(=O)O[C@@H]1CCOC1)S(=O)(=O)c1ccc(N)cc1.[Ca+2]