Hydrocortisone Hemisuccinate Hydrate

CAS: 83784-20-7

Ref. TR-H714765

Product Information

• Name: Hydrocortisone Hemisuccinate Hydrate
• Synonyms: Pregn-4-ene-3,20-dione, 21-(3-carboxy-1-oxopropoxy)-11,17-dihydroxy-, hydrate (1:1), (11ß)-, Pregn-4-ene-3,20-dione, 21-(3-carboxy-1-oxopropoxy)-11,17-dihydroxy-, monohydrate, (11ß)- (9CI), Hydrocortisone hydrogen succinate monohydrate, Hydrocortisone hemisuccinate monohydrate, (11b-)-21-(3-Carboxy-1-oxopropoxy)-11,17-dihydroxypregn-4-ene-3,20-dione monohydrate

Description

Applications Hydrocortisone Hemisuccinate Hydrate is a metabolite of Hydrocortisone (H714615), a steroid hormone, specifically a glucocorticoid, produced by the zona fasciculata of the adrenal gland. Cortisol is released in response to stress and a low level of blood glucocorticoids.
References Vigore, L., et al.: Cancer Ther., 6, 699 (2008); Puurunen, J., et al.: J. Clin. Endocrinol. Metab., 94, 1973 (2009); Lemos, D., et al.: J. Endocrinol., 201, 275 (2009); Chen, S., et al.: Am. J. Physiol., 296 (2009);

• Brand: TRC

Chemical properties

• Molecular weight: 480.55
• Formula: C₂₅H₃₄O₈·H₂O
• Color/Form: White To Off-White
• InChI: InChI=1S/C25H34O8.H2O/c1-23-9-7-15(26)11-14(23)3-4-16-17-8-10-25(32,24(17,2)12-18(27)22(16)23)19(28)13-33-21(31)6-5-20(29)30;/h11,16-18,22,27,32H,3-10,12-13H2,1-2H3,(H,29,30);1H2/t16-,17-,18-,22+,23-,24-,25-;/m0./s1
• InChI key: InChIKey=AFLWPAGYTPJSEY-CODXZCKSSA-N
• SMILES: C[C@]12C[C@H](O)[C@H]3[C@@H](CCC4=CC(=O)CC[C@@]43C)[C@@H]1CC[C@]2(O)C(=O)COC(=O)CCC(=O)O.O