6beta-Hydroxy Budesonide-d8

CAS: 88411-77-2

Ref. TR-H830352

Product Information

• Name: 6beta-Hydroxy Budesonide-d8
• Synonyms: (6β,11β,16α)-16,17-[(Butylidene-d8)bis(oxy)]-6,11,21-trihydroxypregna-1,4-diene- 3,20-dione
• Brand: TRC

Description

Applications A labelled metabolite of Budesonide (B689490), a non-halogenated glucocorticoid related to triamcinolone hexacetonide. Used as an antiinflammatory agent.
References Ryrfeldt., A., et a.: J. Steroid Biochem., 10, 317 (1979), Roth, G., et al.: J. Pharm. Sci., 69, 766 (1980), Edsbaecker, S., et al.: Drug Metab. Dispos., 15, 412 (1987),

Chemical properties

• Molecular weight: 454.58
• Formula: C₂₅H₂₆D₈O₇
• Purity: ~90%
• Color/Form: Neat
• InChI: InChI=1S/C25H34O7/c1-4-5-21-31-20-10-15-14-9-17(28)16-8-13(27)6-7-23(16,2)22(14)18(29)11-24(15,3)25(20,32-21)19(30)12-26/h6-8,14-15,17-18,20-22,26,28-29H,4-5,9-12H2,1-3H3/t14-,15-,17+,18-,20+,21?,22+,23-,24-,25+/m0/s1/i1D3,4D2,5D2,21D
• InChI key: InChIKey=JBVVDXJXIDYDMF-WQDZGEDMSA-N
• SMILES: [2H]C([2H])([2H])C([2H])([2H])C([2H])([2H])C1([2H])O[C@@H]2C[C@H]3[C@@H]4C[C@@H](O)C5=CC(=O)C=C[C@]5(C)[C@H]4[C@@H](O)C[C@]3(C)[C@]2(C(=O)CO)O1