25-Hydroxy Cholesterol-d6

CAS: 88247-69-2

Ref. TR-H918032

Product Information

• Name: 25-Hydroxy Cholesterol-d6
• Synonyms: Cholest-5-ene-26,26,26,27,27,27-d6-3,25-diol, (3ß)-, (3ß)-Cholest-5-ene-26,26,26,27,27,27-d6-3,25-diol, 26,26,26,27,27,27-Hexadeuterio-25-hydroxy-5-cholestene-3ß-ol, 25-Hydroxycholesterol-26,26,26,27,27,27-D6, 5-Cholesten-3ß,25-diol-26,26,26,27,27,27-d6

Description

Applications 25-Hydroxy Cholesterol-d6, is the labeled analogue of 25-Hydroxy Cholesterol (H918030), which is an oxygenated derivative of Cholesterol (C432501); an oxysterol. An inhibitor of human immunodeficiency virus replication in vitro. It also induces apoptosis in human monocytic cell lines as well as inducing apoptosis in CEM cells associated with negative regulation of c-Myc.
References Aupeix, K. et al.: Immunobiology, 194, 415 (1995); Moog, C. et al.: Antivir. Chem, Chemother., 9, 491 (1998); Ayala-Torres, S. et al.: Exp. Cell Res., 246, 193 (1999);

• Brand: TRC

Chemical properties

• Molecular weight: 408.69
• Formula: C₂₇H₆H₄₀O₂
• Color/Form: Neat
• InChI: InChI=1S/C27H46O2/c1-18(7-6-14-25(2,3)29)22-10-11-23-21-9-8-19-17-20(28)12-15-26(19,4)24(21)13-16-27(22,23)5/h8,18,20-24,28-29H,6-7,9-17H2,1-5H3/t18-,20+,21+,22-,23+,24+,26+,27-/m1/s1/i2D3,3D3
• InChI key: InChIKey=INBGSXNNRGWLJU-KHKDDIDZSA-N
• SMILES: [2H]C([2H])([2H])C(O)(CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@@]21C)C([2H])([2H])[2H]