Estimated delivery in United States, on Friday 27 Dec 2024
Product Information
Name:
Hydroxy Fasudil Hydrochloride
Controlled Product
Synonyms:
- 5-(1,4-diazepan-1-ylsulfonyl)isoquinolin-1-ol;hydrochloride
- 5-[(Hexahydro-1H-1,4-diazepin-1-yl)sulfonyl]-1(2H)-isoquinolinone
- Hydroxyfasudil Hydrochloride
- 1-(1-Hydroxy-5-Isoquinolinesulfonyl)Homopiperazine Monohydrochloride
Description:
Applications A metabolite of Fasudil. A cell-permeable, hydroxylated metabolite of HA 1077 that displays anti-anginal properties. Reported to inhibit the Rho kinase-mediated (ROCK) contraction both in vitro and in vivo.
References Shimokawa, H., et al.: Cardiovasc. Res., 43, 1029 (1999), Takemoto, M., et al.: Circulation, 106, 57 (2002), Ito, K., et al.: J. Physiol., 546, 823 (2003),
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
343.83
Formula:
C14H17N3O3S·ClH
Color/Form:
Neat
InChI:
InChI=1S/C14H17N3O3S.ClH/c18-14-12-3-1-4-13(11(12)5-7-16-14)21(19,20)17-9-2-6-15-8-10-17;/h1,3-5,7,15H,2,6,8-10H2,(H,16,18);1H
InChI key:
InChIKey=XWWFOUVDVJGNNG-UHFFFAOYSA-N
SMILES:
Cl.O=S(=O)(c1cccc2c(O)nccc12)N1CCCNCC1
MDL:
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EINECS:
Merck:
HS code:
Technical inquiry about: TR-H942380 Hydroxy Fasudil Hydrochloride
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