Product Information
- (E)-4-[4-[2-(dimethylamino)ethoxy]phenyl]-3,4-diphenylbut-3-en-2-ol
- (βE)-β-[[4-[2-(Dimethylamino)ethoxy]phenyl]phenylmethylene]-α-methylbenzeneethanol
- Benzeneethanol, β-[[4-[2-(dimethylamino)ethoxy]phenyl]phenylmethylene]-α-methyl-, (E)-
- α-Hydroxytamoxifen
- Benzeneethanol, β-[[4-[2-(dimethylamino)ethoxy]phenyl]phenylmethylene]-α-methyl-, (βE)-
Applications A metabolite of the chemotherapeutic drug Tamoxifen (T006000). Exhibits a more potent estrogen agonist/antagonist activity than the parent drug. Also active as an intramembranous inhibitor of lipid peroxidation.
References Kupfer, D., et al.: Cancer Res., 54, 3140 (1994), Custodio, J.B.A., et al.: Biochem. Pharmacol., 47, 1989 (1994),
Chemical properties
Technical inquiry about: TR-H954700 (E)-a-Hydroxy Tamoxifen
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