Ibudilast-d7

CAS: 50847-11-5

Ref. TR-I125003

Product Information

• Name: Ibudilast-d7
• Synonyms: 2-Methyl-1-[2-(1-methylethyl)pyrazolo[1,5-a]pyridin-3-yl]-1-propanone-d7, 1-(2-Isopropylpyrazolo[1,5-a]pyridin-3-yl)-2-methylpropan-1-one-d7, 2-Isopropyl-d7-3-isobutyrylpyrazolo[1,5-a]pyridine, 3-Isobutyryl-d7-2-isopropylpyrazolo[1,5-a]pyridine, AV 411-d7, KC 404-d7, Ketas-d7, 1-(2-Isopropylpyrazolo[1,5-a]pyridin-3-yl)-2-methylpropan-1-one, 1-Propanone, 2-methyl-1-[2-(1-methylethyl)pyrazolo[1,5-a]pyridin-3-yl]-, 2-Isopropyl-3-isobutyrylpyrazolo[1,5-a]pyridine, 2-Methyl-1-(2-propan-2-ylpyrazolo[1,5-a]pyridin-3-yl)propan-1-one, 2-Methyl-1-[2-(1-methylethyl)pyrazolo[1,5-a]pyridin-3-yl]-1-propanone, 2-Methyl-1-[2-(Propan-2-Yl)Pyrazolo[1,5-A]Pyridin-3-Yl]Propan-1-One, 3-Isobutyryl-2-isopropylpyrazolo[1,5-a]pyridine, Av 411, Kc 404, Ketas, Pinatos, Pyrazolo[1,5-a]pyridine, 1-propanone deriv.

Description

Applications Ibudilast-d7 is the labeled analogue of Ibudilast (I125000), a leukotriene D4 antagonist. Used as an antiallergic, antiasthmatic, and vasodilator (cerebral).
References Nishino, K., et al.: Japan J. Pharmacol., 33, 267 (1983); Ohashi, M., et al.: Arch. Int. Pharmacodyn., 280, 216 (1986); Armstead, W.M., et al.: J. Pharmacol., Exp. Ther., 244, 138 (1988)

• Brand: TRC

Chemical properties

• Molecular weight: 237.35
• Formula: C₁₄H₁₁D₇N₂O
• Color/Form: Neat
• InChI: InChI=1S/C14H18N2O/c1-9(2)13-12(14(17)10(3)4)11-7-5-6-8-16(11)15-13/h5-10H,1-4H3/i3D3,4D3,10D
• InChI key: InChIKey=ZJVFLBOZORBYFE-YDQCIOQBSA-N
• SMILES: [2H]C([2H])([2H])C([2H])(C(=O)c1c(C(C)C)nn2ccccc12)C([2H])([2H])[2H]