Product Information
Name:K02288
Controlled Product
Synonyms:
- 3-[6-Amino-5-(3,4,5-trimethoxyphenyl)-3-pyridinyl]-phenol
Brand:TRC
Description:Applications K02288 is a potent and selective type 1 BMP (bone morphogenetic protein) receptor inhibitor with in vitro activity against ALK-2 (activin receptor-like kinase-2) at low nanomolar concentrations. K02288 also inhibits the BMP-induced Smad pathway without affecting TGF-β signaling and induces dorsalization of zebrafish embryos.References Sanvitale, C.E., et al.: PLoS One, 8, e62721 (2013)
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:352.38
Formula:C20H20N2O4
Color/Form:Neat
InChI:InChI=1S/C20H20N2O4/c1-24-17-9-13(10-18(25-2)19(17)26-3)16-8-14(11-22-20(16)21)12-5-4-6-15(23)7-12/h4-11,23H,1-3H3,(H2,21,22)
InChI key:InChIKey=CJLMANFTWLNAKC-UHFFFAOYSA-N
SMILES:COc1cc(-c2cc(-c3cccc(O)c3)cnc2N)cc(OC)c1OC
Technical inquiry about: K02288
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