all-trans 4-Keto Retinoic Acid-(9-methyl)-d3 (>85%)

CAS: 1346606-26-5

Ref. TR-K204983

Product Information

• Name: all-trans 4-Keto Retinoic Acid-(9-methyl)-d3 (>85%)
• Synonyms: 4-Oxoretinoic-(9-methyl-d3) acid, 4-Ketoretinoic acid (9-methyl-D3), 4-Oxo-all-trans-retinoic-d3 acid, 4-Oxotretinoin-d3, 4-keto-Retinoic acid-d3, all-trans-4-Oxoretinoic acid-d3, (2E,4E,6E,8E)-3-Methyl-7-(methyl-d3)-9-(2,6,6-trimethyl-3-oxocyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid
• Brand: TRC

Description

Stability Light Sensitive
Applications A deuterated metabolite of all-trans-Retinoic Acid, a ligand for both the retinoic acid receptor (RAR) and the retinoid X receptor (RXR).
References Andreola, F., et al.: J. Biol. Chem., 279, 3434 (2004), Armstrong, J., et al.: Biochem. Pharmacol., 69, 1299 (2005), Njar, V., et al.: Bioorg. Med. Chem., 14, 4323 (2006), Veal, G., et al.: Br. J. Cancer, 96, 424 (2007),

Chemical properties

• Molecular weight: 317.44
• Formula: C₂₀₂H₃H₂₃O₃
• Purity: >85%
• Color/Form: Neat
• InChI: InChI=1S/C20H26O3/c1-14(7-6-8-15(2)13-19(22)23)9-10-17-16(3)18(21)11-12-20(17,4)5/h6-10,13H,11-12H2,1-5H3,(H,22,23)/b8-6+,10-9+,14-7+,15-13+/i1D3
• InChI key: InChIKey=GGCUJPCCTQNTJF-LMOMAJEASA-N
• SMILES: [2H]C([2H])([2H])C(/C=C/C1=C(C)C(=O)CCC1(C)C)=C\C=C\C(C)=C\C(=O)O