Product Information
Name:LB 42708
Controlled Product
Synonyms:
- [1-[[3-[(4-bromophenyl)methyl]imidazol-4-yl]methyl]-4-naphthalen-1-ylpyrrol-3-yl]-morpholin-4-ylmethanone
Brand:TRC
Description:Applications LB 42708 is a selective nonpeptidic Farnesyltransferase (FTase) inhibitor.LB42708 suppresses tumor growth and tumor angiogenesis in both xenograft tumor models of Ras-mutated HCT116 cells and its wild-type Caco-2 cells, indicating its potential application in the treatment of both Ras-mutated and wild type tumors.References Kim, C., et. al.: Mol. Pharmacol., 78, 142 (2010)
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:555.46
Formula:C30H27BrN4O2
Color/Form:Neat
InChI:InChI=1S/C30H27BrN4O2/c31-24-10-8-22(9-11-24)17-35-21-32-16-25(35)18-33-19-28(27-7-3-5-23-4-1-2-6-26(23)27)29(20-33)30(36)34-12-14-37-15-13-34/h1-11,16,19-21H,12-15,17-18H2
InChI key:InChIKey=GUUIRIMAQGOLHT-UHFFFAOYSA-N
SMILES:O=C(c1cn(Cc2cncn2Cc2ccc(Br)cc2)cc1-c1cccc2ccccc12)N1CCOCC1
Technical inquiry about: LB 42708
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