Product Information
Name:LGK 974
Controlled Product
Synonyms:
- 2',3-Dimethyl-N-[5-(2-pyrazinyl)-2-pyridinyl]-[2,4'-bipyridine]-5-acetamide
- 2-(2',3-Dimethyl-[2,4'-bipyridin]-5-yl)-N-(5-(pyrazin-2-yl)pyridin-2-yl)acetamide
Brand:TRC
Description:Applications LGK 974 is a potent and specific small molecule Porcupine (PORCN) inhibitor.References Liu, J., et. al.: Roc. Natl. Acad. Sci. USA, 110, 20224 (2013)
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:396.44
Formula:C23H20N6O
Color/Form:Neat
InChI:InChI=1S/C23H20N6O/c1-15-9-17(12-28-23(15)18-5-6-25-16(2)10-18)11-22(30)29-21-4-3-19(13-27-21)20-14-24-7-8-26-20/h3-10,12-14H,11H2,1-2H3,(H,27,29,30)
InChI key:InChIKey=XXYGTCZJJLTAGH-UHFFFAOYSA-N
SMILES:Cc1cc(-c2ncc(CC(=O)Nc3ccc(-c4cnccn4)cn3)cc2C)ccn1
Technical inquiry about: LGK 974
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