Lorazepam

CAS: 846-49-1

Ref. TR-L469850

Product Information

• Name: Lorazepam
• Synonyms: 2H-1,4-Benzodiazepin-2-one, 7-chloro-5-(o-chlorophenyl)-1,3-dihydro-3-hydroxy- (7CI,8CI), (RS)-Lorazepam, 7-Chloro-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4-benzodiazepin-2-one, 7-Chloro-5-(o-chlorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4-benzodiazepin-2-one, Almazine, Anxiedin, Anxira, Anzepam, Aplacasse, Aplacassee, Apo-Lorazepam, Aripax, Ativan, Azurogen, Bonatranquan, Bonton, Control, Delormetazepam, Demethyllormetazepam, Duralozam, Efasedan, Emotival, Equitam, Kalmalin, Larpose, Laubeel, Lopam, Lorabenz, Loram, Lorans, Lorapam, Lorat, Lorax, Lorazene, Lorazep, Lorazin, Lorazon, Lorenin, Loridem, Lorivan, Lorsedal, Lorsilan, Lorzem, Lozepam, Merlit, NIC, NSC 289758, Nervistop L, Norlormetazepam, Novhepar, Novo-lorazem, Orfidal, Pro Dorm, Psicopax, Punktyl, Quait, Renaquil, Reposepan, Rocosgen, Securit, Sedatival, Sedazin, Sedizepan, Sidenar, Silence, Sinestron, Somagerol, Stapam, Tavor, Tavor Expidet, Temesta, Titus, Tranqipam, Trapax, Trapex, Upan, Wintin, Wy 4036, Wypax, o-Chlorooxazepam, o-Chloroxazepam, (.+-.)-Lorazepam, 2H-1,4-Benzodiazepin-2-one, 7-chloro-5-(o-chlorophenyl)-1,3-dihydro-3-hydroxy-, 7-Chloro-5-(2-chlorophenyl)-3-hydroxy-1H-1,4-benzodiazepin-2(3H)-one, Lorazem, Nsc 289758
• CAS: 846-49-1

Description

Impurity Lorazepam USP Related Compound A
Stability hygroscopic
Applications Lorazepam is an anxiolytic compound that potentiates GABAergic synaptic transmission by binding at the benzodiazepine site on the GABAA receptor.1,2 This product is intended for forensic and research applications. Lorazepam acts as ananticonvulsant. Lorazepam USP Related Compound A.Controlled substance (depressant).
References Rutgers, G., et al.: Anal. Profiles Drug Subs., 9, 397 (1980), Korkmaz, S., et al.: Eur. Neuropsychopharmacol., 8, 175 (1998), D’Onofrio, G., et al.: N. Engl. J. Med., 340, 915 (1999),

• Brand: TRC

Chemical properties

• Molecular weight: 321.16
• Formula: C₁₅H₁₀Cl₂N₂O₂
• Color/Form: White to Pale Yellow Solid
• InChI: InChI=1S/C15H10Cl2N2O2/c16-8-5-6-12-10(7-8)13(19-15(21)14(20)18-12)9-3-1-2-4-11(9)17/h1-7,15,21H,(H,18,20)
• InChI key: InChIKey=DIWRORZWFLOCLC-UHFFFAOYSA-N
• SMILES: O=C1Nc2ccc(Cl)cc2C(c2ccccc2Cl)=NC1O