CAS 846-49-1
:2H-1,4-Benzodiazepin-2-one, 7-chloro-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-
Description:
The chemical substance known as 2H-1,4-Benzodiazepin-2-one, 7-chloro-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy- (CAS number 846-49-1) is a member of the benzodiazepine family, which is characterized by a fused benzene and diazepine ring structure. This compound typically exhibits psychoactive properties, often functioning as a central nervous system depressant. Its structure includes a chloro substituent at the 7-position and a 2-chlorophenyl group at the 5-position, which can influence its pharmacological activity and potency. The presence of a hydroxy group at the 3-position contributes to its chemical reactivity and potential interactions with biological targets. Benzodiazepines are commonly used for their anxiolytic, sedative, and muscle relaxant effects, although they may also pose risks of dependence and withdrawal. The specific characteristics, such as solubility, melting point, and stability, can vary based on the compound's formulation and purity. As with all chemical substances, proper handling and safety precautions are essential due to potential toxicity and regulatory considerations.
Formula:C15H10Cl2N2O2
InChI:InChI=1/C15H10Cl2N2O2/c16-8-5-6-12-10(7-8)13(19-15(21)14(20)18-12)9-3-1-2-4-11(9)17/h1-7,15,21H,(H,18,20)
InChI key:InChIKey=DIWRORZWFLOCLC-UHFFFAOYSA-N
SMILES:ClC1=C(C=2C=3C(NC(=O)C(O)N2)=CC=C(Cl)C3)C=CC=C1
Synonyms:- (.+-.)-Lorazepam
- (RS)-Lorazepam
- 2H-1,4-Benzodiazepin-2-one, 7-chloro-5-(o-chlorophenyl)-1,3-dihydro-3-hydroxy-
- 7-Chloro-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4-benzodiazepin-2-one
- 7-Chloro-5-(2-chlorophenyl)-3-hydroxy-1H-1,4-benzodiazepin-2(3H)-one
- 7-Chloro-5-(o-chlorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4-benzodiazepin-2-one
- Almazine
- Anxiedin
- Anxira
- Anzepam
- Aplacasse
- Aplacassee
- Apo-Lorazepam
- Aripax
- Ativan
- Azurogen
- Bonatranquan
- Bonton
- Control
- Delormetazepam
- Demethyllormetazepam
- Duralozam
- Efasedan
- Emotival
- Equitam
- Kalmalin
- Larpose
- Laubeel
- Lopam
- Lorabenz
- Loram
- Lorans
- Lorapam
- Lorat
- Lorax
- Lorazem
- Lorazene
- Lorazep
- Lorazin
- Lorazon
- Lorenin
- Loridem
- Lorivan
- Lorsedal
- Lorsilan
- Lorzem
- Lozepam
- Merlit
- NIC
- Nervistop L
- Norlormetazepam
- Novhepar
- Novo-lorazem
- Nsc 289758
- Orfidal
- Pro Dorm
- Psicopax
- Punktyl
- Quait
- Renaquil
- Reposepan
- Rocosgen
- Securit
- Sedatival
- Sedazin
- Sedizepan
- Sidenar
- Silence
- Sinestron
- Somagerol
- Stapam
- Tavor
- Tavor Expidet
- Temesta
- Titus
- Tranqipam
- Trapax
- Trapex
- Upan
- Wintin
- Wy 4036
- Wypax
- o-Chlorooxazepam
- o-Chloroxazepam
- 2H-1,4-Benzodiazepin-2-one, 7-chloro-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-
- (+-)-lorazepam--dea schedule iv item
- 1,4-benzodiazepin-2-one,7-chloro-5-(o-chlorophenyl)-1,3-dihydro-3-hydroxy-2
- AURORA KA-7219
- 7-Chloro-5-(2-chlorophenyl)-3-hydroxy-1,3-dihydro-2H-1,4-benzodiazepin-2-one
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Lorazepam
CAS:Controlled ProductFormula:C15H10Cl2N2O2Color and Shape:White CrystallineMolecular weight:321.16Lorazepam, 1mg/ml in Acetonitrile
CAS:Controlled ProductFormula:C15H10Cl2N2O2Color and Shape:ColourlessMolecular weight:321.16Lorazepam 1.0 mg/ml in Acetonitrile
CAS:Controlled ProductFormula:C15H10Cl2N2O2Color and Shape:ColourlessMolecular weight:321.16Lorazepam
CAS:Controlled ProductImpurity Lorazepam USP Related Compound A
Stability hygroscopic
Applications Lorazepam is an anxiolytic compound that potentiates GABAergic synaptic transmission by binding at the benzodiazepine site on the GABAA receptor.1,2 This product is intended for forensic and research applications. Lorazepam acts as ananticonvulsant. Lorazepam USP Related Compound A.Controlled substance (depressant).
References Rutgers, G., et al.: Anal. Profiles Drug Subs., 9, 397 (1980), Korkmaz, S., et al.: Eur. Neuropsychopharmacol., 8, 175 (1998), D’Onofrio, G., et al.: N. Engl. J. Med., 340, 915 (1999),Formula:C15H10Cl2N2O2Color and Shape:NeatMolecular weight:321.16Lorazepam
CAS:Controlled ProductLorazepam is a benzodiazepine that binds to the benzodiazepine receptor in the central nervous system. This binding induces a variety of effects, including sedation, muscle relaxation, and suppression of anxiety. Lorazepam can be used as an antianxiety agent and as an adjunct to anesthesia. Lorazepam is metabolized by oxidation at the 3-position to produce lorazepam-3-glucuronide (LZG), which is excreted in urine. The major metabolic pathway involves glucuronidation followed by biliary excretion of LZG. Benzalkonium chloride has been used for analytical purposes in chromatographic analysis with minimal toxicity.Formula:C15H10Cl2N2O2Purity:Min. 95%Color and Shape:Slightly Yellow PowderMolecular weight:321.16 g/molLORAZEPAM CRS - * PSY
CAS:Controlled ProductLORAZEPAM CRS - * PSYFormula:C15H10Cl2N2O2Color and Shape:Crystalline Powder. White. Powder.Molecular weight:321.1581LORAZEPAM FOR SYSTEM SUITABILITY CRS - * PSY (LORAZEPAM)
CAS:Controlled ProductLORAZEPAM FOR SYSTEM SUITABILITY CRS - * PSY (LORAZEPAM)Formula:C15H10Cl2N2O2Molecular weight:321.1581Lorazepam
CAS:Controlled ProductLorazepamFormula:C15H10Cl2N2O2Purity:99.7%Color and Shape:White CrystallineMolecular weight:320.01193Lorazepam (1.0 mg/mL in Acetonitrile)
CAS:Controlled ProductFormula:C15H10Cl2N2O2Color and Shape:Single SolutionMolecular weight:321.16Lorazepam (100 ug/mL in Acetonitrile)
CAS:Controlled ProductFormula:C15H10Cl2N2O2Color and Shape:Single SolutionMolecular weight:321.16Lorazepam
CAS:Controlled ProductAlprazolam(inn), camazepam (inn), chlordiazepoxide (inn), clonazepam (inn), clorazepate & other heterocyclic compounds with nitro atom(s) onlyFormula:C15H10Cl2N2O2Color and Shape:White Off-White Crystalline PowderMolecular weight:320.01193








