Loxapine, Succinate

CAS: 27833-64-3

Ref. TR-L472750

Product Information

• Name: Loxapine, Succinate
• Synonyms: 2-Chloro-11-(4-methyl-1-piperazinyl)dibenz[b,f][1,4]oxazepine butanedioate, Succinic acid, compd. with 2-chloro-11-(4-methyl-1-piperazinyl)dibenz[b,f][1,4]oxazepine, Dibenz[b,f][1,4]oxazepine, 2-chloro-11-(4-methyl-1-piperazinyl)-, butanedioate, 2-Chloro-11-(4-methyl-1-piperazinyl)-dibenz[b,f][1,4]oxazepine succinate, CL 71563, Daxolin, Loxapac, Loxitane
• Brand: TRC
• Description: Applications A D2/D4-Dopamine receptor antagonist. A serotonergic receptor antagonist. A dibenzoxazepine antipsychotic agent.References Shen, Y., et al.: J. Biol. Chem., 268, 18200 (1993), Fiorella, D., et al.: Psychopharmacology, 121, 347 (1995), Glusa, E., et al.: Br. J. Pharmacol., 130, 692 (2000)

Chemical properties

• Molecular weight: 445.90
• Formula: C₁₈H₁₈ClN₃O·C₄H₆O₄
• Color/Form: White
• InChI: InChI=1S/C18H18ClN3O.C4H6O4/c1-21-8-10-22(11-9-21)18-14-12-13(19)6-7-16(14)23-17-5-3-2-4-15(17)20-18;5-3(6)1-2-4(7)8/h2-7,12H,8-11H2,1H3;1-2H2,(H,5,6)(H,7,8)
• InChI key: InChIKey=YQZBAXDVDZTKEQ-UHFFFAOYSA-N
• SMILES: CN1CCN(C2=Nc3ccccc3Oc3ccc(Cl)cc32)CC1.O=C(O)CCC(=O)O