Manidipine Dihydrochloride

CAS: 89226-75-5

Ref. TR-M164015

Product Information

• Name: Manidipine Dihydrochloride
• Synonyms: 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 3-[2-[4-(diphenylmethyl)-1-piperazinyl]ethyl] 5-methyl ester, hydrochloride (1:2), 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 2-[4-(diphenylmethyl)-1-piperazinyl]ethyl methyl ester, dihydrochloride (9CI), CV 4093, Calslot, Franidipine hydrochloride
• Brand: TRC
• Description: Applications Manidipine Dihydrochloride is a metabolite of Manidipine (M164000), a dihydropyridine calcium channel blocker that exhibits antihypertensive properties. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the packageReferences Meguro, K., et al.: Chem. Pharm. Bull., 33, 3787 (1985), Mizuno, K., et al.: Curr. Ther. Res., 52, 248 (1992); Hosaka, S., et al.: Chem. Pharma. Bulletin., 55, 793 (2007)

Chemical properties

• Molecular weight: 683.6213
• Formula: C₃₅H₃₈N₄O₆·2ClH
• Color/Form: Neat
• InChI: InChI=1S/C35H38N4O6.2ClH/c1-24-30(34(40)44-3)32(28-15-10-16-29(23-28)39(42)43)31(25(2)36-24)35(41)45-22-21-37-17-19-38(20-18-37)33(26-11-6-4-7-12-26)27-13-8-5-9-14-27;;/h4-16,23,32-33,36H,17-22H2,1-3H3;2*1H
• SMILES: COC(=O)C1=C(C)NC(C)=C(C(=O)OCCN2CCN(C(c3ccccc3)c3ccccc3)CC2)C1c1cccc([N+](=O)[O-])c1.Cl.Cl