Methyl (1R,4S)-4-[[(1,1-Dimethylethoxy)carbonyl]amino]-2-cyclopentene-1-carboxylic Acid Ester

CAS: 251326-99-5

Ref. TR-M220430

Product Information

• Name: Methyl (1R,4S)-4-[[(1,1-Dimethylethoxy)carbonyl]amino]-2-cyclopentene-1-carboxylic Acid Ester
• Synonyms: Methyl (1R,4S)-4-[(tert-Butoxycarbonyl)amino]cyclopent-2-ene-1-carboxylate, Methyl (1R,4S)-4-(tert-Butoxycarbonylamino)cyclopent-2-ene-1-carboxylate, (1R,4S)-Methyl 4-[(tert-Butoxycarbonyl)amino]cyclopent-2-enecarboxylate
• Brand: TRC

Description

Applications Methyl (1R,4S)-4-[[(1,1-Dimethylethoxy)carbonyl]amino]-2-cyclopentene-1-carboxylic Acid Ester is used in the discovery of a potent, selective and orally bioavailable dual CCR2 and CCR5 antagonist.
References Zheng, C., et al.: Bioorg. Med. Chem. Lett., 21, 1442-1446 (2011)

Chemical properties

• Molecular weight: 241.284
• Formula: C₁₂H₁₉NO₄
• Color/Form: Neat
• InChI: InChI=1S/C12H19NO4/c1-12(2,3)17-11(15)13-9-6-5-8(7-9)10(14)16-4/h5-6,8-9H,7H2,1-4H3,(H,13,15)/t8-,9+/m0/s1
• InChI key: InChIKey=HKLDTKMTZPXEAZ-DTWKUNHWSA-N
• SMILES: COC(=O)[C@H]1C=C[C@@H](NC(=O)OC(C)(C)C)C1