1-[1-(4-Methoxyphenyl)-2-(methylamino)ethyl]cyclohexanol Hydrochloride(rac N-Desmethyl Venlafaxine Hydrochloride)

CAS: 93413-90-2

Ref. TR-M266250

Product Information

• Name: 1-[1-(4-Methoxyphenyl)-2-(methylamino)ethyl]cyclohexanol Hydrochloride(rac N-Desmethyl Venlafaxine Hydrochloride)
• Synonyms: Venlafaxine Hydrochloride Imp. D (EP) as Hydrochloride, N-Desmethylvenlafaxine Hydrochloride,1-[(1RS)-1-(4-Methoxyphenyl)-2-(methylamino)ethyl]cyclohexanol Hydrochloride
• Brand: TRC

Description

Impurity Venlafaxine EP Impurity D; Venlafaxine USP Related Compound A
Applications 1-[1-(4-Methoxyphenyl)-2-(methylamino)ethyl]cyclohexanol Hydrochloride (Venlafaxine EP Impurity D; Venlafaxine USP Related Compound A) is a metabolite of Venlafaxine (V120000), which is a selective serotonin noradrenaline reuptake inhibitor, used as an antidepressant.
References Klamerus, K. J., et al.: J. Clin. PHarmacol., 32, 716 (1992), Gelenberg, A.J., et al.: J. Am. Med. Assoc., 283, 3082 (2000);

Chemical properties

• Molecular weight: 299.84
• Formula: C₁₆H₂₅NO₂·ClH
• Color/Form: Neat
• InChI: InChI=1S/C16H25NO2.ClH/c1-17-12-15(16(18)10-4-3-5-11-16)13-6-8-14(19-2)9-7-13;/h6-9,15,17-18H,3-5,10-12H2,1-2H3;1H
• InChI key: InChIKey=HWPAFKGYJZARRM-UHFFFAOYSA-N
• SMILES: CNCC(c1ccc(OC)cc1)C1(O)CCCCC1.Cl