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3-Methyl Adenine

CAS:

Ref. TR-M275904

3-Methyl Adenine
TRC

Product Information

Name:3-Methyl Adenine
Synonyms:
  • 3-Methyl-3H-purin-6-amine
  • 3-Methyl-6-aminopurine
  • 3-Methyladenine
  • 6-Amino-3-methylpurine
  • N3-Methyladenine
  • NSC 66389
Brand:TRC
Description:

Applications 3-Methyl Adenine is a selective autophagy and phosphoinositide 3-kinase (PI3K) inhibitor (1,2,3). 3-MA inhibits autophagy by blocking autophagosome formation via the inhibition of type III Phosphatidylinositol 3-kinases (PI-3K).
References (1) Munafo, D., et al.: J. Cell Sci., 114, 3619 (2001) (2) Aggarwal, B., et al.: Biochem. Pharmacol., 71, 1397 (2006) (3) Hayat, M., et al.: Oncologist, 12, 20 (2007)

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Chemical properties

Molecular weight:149.15
Formula:C6H7N5
Color/Form:Neat
InChI:InChI=1S/C6H7N5/c1-11-3-10-5(7)4-6(11)9-2-8-4/h2-3H,7H2,1H3
InChI key:InChIKey=FSASIHFSFGAIJM-UHFFFAOYSA-N
SMILES:Cn1cnc(N)c2ncnc1-2

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