6-Methyl-2-thiouracil

CAS: 56-04-2

Ref. TR-M331355

Product Information

• Name: 6-Methyl-2-thiouracil
• Synonyms: 4(1H)-Pyrimidinone, 2,3-dihydro-6-methyl-2-thioxo-, Uracil, 6-methyl-2-thio- (8CI), 2-Mercapto-4-methyl-6-hydroxypyrimidine, 2-Mercapto-6-methyl-4-pyrimidinol, 2-Mercapto-6-methylpyrimidin-4-one, 2-Mercapto-6-methylpyrimidyl-4-one, 2-Thio-6-methyluracil, 4-Hydroxy-2-mercapto-6-methylpyrimidine, 4-Hydroxy-6-methyl-2-mercaptopyrimidine, 4-Hydroxy-6-methylpyrimidine-2(1H)-thione, 4-Methyl-2-thiouracil, 6-Methyl-2-mercaptouracil, 6-Methyl-2-thio-2,4-(1H,3H)-pyrimidinedione, 6-Methyl-4-oxo-2-thioxo-1,2,3,4-tetrahydropyrimidine, 6-Thio-4-methyluracil, Alkiron, Antibason, Basecil, Basethyrin, MTU, Metacil, Methacil, Methiacil, Methicil, Methiocil, Methylthiouracil, Metiur, Muracil, Muracin, NSC 193526, NSC 314271, NSC 9378, Orcanon, Prostrumyl, Strumacil, Thimecil, Thiomecil, Thiomidil, Thioryl, Thiothymin, Thiothyron, Thiuryl, Thyreonorm, Thyril, Tiomeracil, Tiorale M, Tiotiron, USAF-EK 6454, 2,3-Dihydro-6-methyl-2-thioxo-4(1H)-pyrimidinone, 2-Mercapto-6-methylpyrimidin-4(3H)-one, 4(1H)-pyrimidinone, 2,3-dihydro-6-methyl-2-thioxo-, 6-(methylsulfanyl)pyrimidine-2,4(1H,3H)-dione, 6-Methyl-2-Sulfanylpyrimidin-4-Ol, 6-Methyl-2-Thiouracyle, 6-Methyl-2-thioxo-2,3-dihydro-4(1H)-pyrimidinone, 6-Methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-on, 6-Methyl-2-thioxopyrimidin-4-one, 6-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one, Methiure, Methylthiouracile, Metiltiouracilo, Nsc 193526, Nsc 314271, Nsc 9378, Thyreostat, Thyreostat I, Uracil, 2-Thio-4-Methyl-, Uracil, 6-methyl-2-thio-, Usaf-Ek 6454

Description

Applications 6-​Methyl-​2-​thiouracil is a derivative of methylthiouracil (M330710), a competitive inhibitor of Nitric Oxide Synthase (NOS). Potential anti-inflammatory agent.
References Palumbo, A. et al.: Biochem. Bioph. Res. Co. 282, 793(2001), Ku, S. et al.: Toxicol. App. Pharmacol., 288, 374 (2015);

• Brand: TRC

Chemical properties

• Molecular weight: 142.18
• Formula: C₅H₆N₂OS
• Color/Form: White
• InChI: InChI=1S/C5H6N2OS/c1-3-2-4(8)7-5(9)6-3/h2H,1H3,(H2,6,7,8,9)
• InChI key: InChIKey=HWGBHCRJGXAGEU-UHFFFAOYSA-N
• SMILES: Cc1cc(=O)[nH]c(=S)[nH]1