4-Methylumbelliferyl a-L-Idopyranosiduronic Acid 2-Sulfate Disodium Salt

CAS: 2181774-46-7

Ref. TR-M334715

Product Information

• Name: 4-Methylumbelliferyl a-L-Idopyranosiduronic Acid 2-Sulfate Disodium Salt
• Synonyms: 4-Methylumbelliferyl ?-L-Iduronic Acid-2-sulfate Sodium Salt, 4-Methyl-2-oxo-2H-1-benzopyran-7-yl ?-L-Idopyranosiduronic Acid 2-(Hydrogen Sulfate)
• Brand: TRC

Description

Stability Hygroscopic
Applications 4-Methylumbelliferyl ?-L-Idopyranosiduronic Acid 2-Sulfate Disodium Salt is a fluorogenic substrate in the assay of ?-L-Iduronidase. A fluorimetric enzyme assay for the diagnosis of MPS II (Hunter disease).
References Matalon, R., et al.: Biochem. Biophys. Res. Commun., 47, 959 (1972), Voznyi, Y.V., et al.: J. Inherit. Metab. Dis., 24, 675 (2001)

Chemical properties

• Molecular weight: 476.32
• Formula: C₁₆H₁₄Na₂O₁₂S
• Color/Form: Neat
• InChI: InChI=1S/C16H16O12S.2Na/c1-6-4-10(17)26-9-5-7(2-3-8(6)9)25-16-14(28-29(22,23)24)12(19)11(18)13(27-16)15(20)21;;/h2-5,11-14,16,18-19H,1H3,(H,20,21)(H,22,23,24);;/q;2*+1/p-2/t11-,12-,13+,14+,16+;;/m0../s1
• InChI key: InChIKey=BGWMBPGUPUSUIU-CEWNINSASA-L
• SMILES: Cc1cc(=O)oc2cc(O[C@@H]3O[C@@H](C(=O)O[Na])[C@@H](O)[C@H](O)[C@H]3OS(=O)(=O)O[Na])ccc12