CAS 2181774-46-7

Formula: C16H14Na2O12S

InChI: InChI=1S/C16H16O12S.2Na/c1-6-4-10(17)26-9-5-7(2-3-8(6)9)25-16-14(28-29(22,23)24)12(19)11(18)13(27-16)15(20)21;;/h2-5,11-14,16,18-19H,1H3,(H,20,21)(H,22,23,24);;/q;2*+1/p-2/t11-,12-,13+,14+,16+;;/m0../s1

InChI key: BGWMBPGUPUSUIU-CEWNINSASA-L

SMILES: CC1=CC(=O)OC2=C1C=CC(=C2)O[C@H]3[C@@H]([C@H]([C@@H]([C@@H](O3)C(=O)[O-])O)O)OS(=O)(=O)[O-].[Na+].[Na+]

Coumarin Impurity 2 Disodium Salt

CAS: 2181774-46-7

Formula: C₁₆H₁₄O₁₂S·2Na

Color and Shape: White To Off-White Solid

Molecular weight: 430.34 2*22.99

Ref: 4Z-C-1633

4-Methylumbelliferyl a-L-Idopyranosiduronic Acid 2-Sulfate Disodium Salt

CAS: 2181774-46-7

Stability Hygroscopic
Applications 4-Methylumbelliferyl ?-L-Idopyranosiduronic Acid 2-Sulfate Disodium Salt is a fluorogenic substrate in the assay of ?-L-Iduronidase. A fluorimetric enzyme assay for the diagnosis of MPS II (Hunter disease).
References Matalon, R., et al.: Biochem. Biophys. Res. Commun., 47, 959 (1972), Voznyi, Y.V., et al.: J. Inherit. Metab. Dis., 24, 675 (2001)

Formula: C₁₆H₁₄Na₂O₁₂S

Color and Shape: Neat

Molecular weight: 476.32

Ref: TR-M334715

4-Methylumbelliferyl a-L-Idopyranosiduronic Acid 2-Sulfate Disodium Salt (≥99%)

Controlled Product

CAS: 2181774-46-7

Formula: C₁₆H₁₄Na₂O₁₂S

Purity: ≥99%

Color and Shape: Neat

Molecular weight: 476.32

Ref: TR-M564880

4-Methylumbelliferyl a-L-idopyranosiduronic acid 2-sulphate disodium salt - Moscerdam™ biochemical purity

CAS: 2181774-46-7

PAIRED PRODUCT AVAILABLE: alpha-L-iduronidase Enzyme, FI1793834MU-alpha-L-iduronide-2-sulphate (M2) is a fluorogenic substrate of iduronate-2-sulphatase (IDS), used in a 2-step assay coupled with alpha-L-iduronidase. The assay is used in biochemical testing for Hunter syndrome (mucopolysaccharidosis II / MPS II). In a first step, IDS from biological samples cleaves the sulphate group from M2. In a second step, exogeneous alpha-L-iduronidase which cleaves the 4-MU moiety is added to the reaction, resulting in release of a fluorescent signal (Ex 360 nm / Em 455 nm). The reaction is stopped by the addition of sodium carbonate.

Formula: C₁₆H₁₄Na₂O₁₂S

Purity: Min. 99 Area-%

Color and Shape: White Powder

Molecular weight: 476.32 g/mol

Ref: 3D-EM03201

4-Methylumbelliferyl-α-L-iduronide 2-sulfate sodium

CAS: 2181774-46-7

4-Methylumbelliferyl-α-L-iduronide 2-sulfate (4-MU-α-idoa 2-sulfate) sodium serves as a fluorescent substrate for iduronate-2-sulfatase (I2S). This compound can be hydrolyzed by the lysosomal enzyme α-L-iduronidase (IDUA), liberating the fluorophore 4-Methylumbelliferone. It is utilized in the detection of Hurler syndrome.

Formula: C₁₆H₁₄Na₂O₁₂S

Color and Shape: Solid

Molecular weight: 476.32

Ref: TM-T211854