4-Methylumbelliferyl α-L-Iduronide (free acid)

CAS: 66966-09-4

Ref. TR-M337643

Product Information

• Name: 4-Methylumbelliferyl α-L-Iduronide (free acid)
• Synonyms: a-L-Idopyranosiduronic acid, 4-methyl-2-oxo-2H-1-benzopyran-7-yl, 4-Methyl-2-oxo-2H-1-benzopyran-7-yl a-L-idopyranosiduronic acid, 4-Methylumbelliferyl a-L-idopyranosiduronic acid, 4-Methylumbelliferyl a-L-iduronide, 4-Methyl-2-oxo-2H-1-benzopyran-7-yl alpha-L-ido-pyranosiduronic acid, 4-Methyl-2-oxo-2H-1-benzopyran-7-yl α-<span class="text-smallcaps">L</span>-idopyranosiduronic acid, 4-Methylumbelliferyl iduronide, 4-Methylumbelliferyl α-<span class="text-smallcaps">L</span>-idopyranosiduronic acid, 4-Methylumbelliferyl α-<span class="text-smallcaps">L</span>-iduronide, 4-methyl-2-oxo-2H-chromen-7-yl alpha-L-idopyranosiduronic acid, alpha-L-Idopyranosiduronic acid, 4-methyl-2-oxo-2H-1-benzopyran-7-yl, α-<span class="text-smallcaps">L</span>-Idopyranosiduronic acid, 4-methyl-2-oxo-2H-1-benzopyran-7-yl, 4-Methylumbelliferyl α-L-iduronide, 4-Methyl-2-oxo-2H-1-benzopyran-7-yl α-L-idopyranosiduronic acid, α-L-Idopyranosiduronic acid, 4-methyl-2-oxo-2H-1-benzopyran-7-yl, 4-Methylumbelliferyl α-L-idopyranosiduronic acid

Description

Stability Hygroscopic
Applications 4-Methylumbelliferyl α-L-Iduronide (free acid) is a fluorogenic substrate for α-L-iduronidase. This product form is the free acid, which offers a considerable weight for weight advantage over the 4-MU iduronide salt in terms of its application dose.
References Baxter, M.A., et al. 2002. Blood. 99: 1857-1859

• Brand: TRC

Chemical properties

• Molecular weight: 352.29
• Formula: C₁₆H₁₆O₉
• Color/Form: Neat
• InChI: InChI=1S/C16H16O9/c1-6-4-10(17)24-9-5-7(2-3-8(6)9)23-16-13(20)11(18)12(19)14(25-16)15(21)22/h2-5,11-14,16,18-20H,1H3,(H,21,22)/t11-,12-,13+,14+,16+/m0/s1
• InChI key: InChIKey=YAYKUKWEFJDSJG-SMEOYISOSA-N
• SMILES: C[C@H]1CC(=O)N2C[C@]34C[C@]5(CC(=O)N(C)C5=O)C(C)(C)[C@@H]3CC12C(=O)N4C