Naltrexone

CAS: 16590-41-3

Ref. TR-N285745

Product Information

• Name: Naltrexone
• Synonyms: 1-N-Cyclopropylmethyl-7,8-dihydro-14-hydroxynormorphinone, Depotrex, EN 1639, N-Cyclopropylmethylnoroxymorphone, Naltrel, Nemexin, Trexonil, UM 792, Vivitrex, Vivitrol, (5alpha)-17-(Cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxymorphinan-6-one, Morphinan-6-one, 17-(cyclopropylmethyl)-4,5alpha-epoxy-3,14-dihydroxy- (8CI),(-)-Naltrexone, (1S,5R,13R,17S)-4-(Cyclopropylmethyl)-10,17-dihydroxy-12-oxa-4-azapentacyclo[9.6.1.0~1,13~.0~5,17~.0~7,18~]octadeca-7(18),8,10-trien-14-on, (1S,5R,13R,17S)-4-(cyclopropylmethyl)-10,17-dihydroxy-12-oxa-4-azapentacyclo[9.6.1.0~1,13~.0~5,17~.0~7,18~]octadeca-7(18),8,10-trien-14-one, (5a)-17-(Cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxymorphinan-6-one, (5alpha)-17-(Cyclopropylmethyl)-3,14-dihydroxy-4,5-epoxymorphinan-6-one, 16590-41-3, En 1639, En 1639A, Morphinan-6-one, 17-(cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxy-, (5α)-, Morphinan-6-one, 17-(cyclopropylmethyl)-4,5α-epoxy-3,14-dihydroxy-, Naltrexon, Naltrexona, ReVia, Um 792

Description

Applications Naltrexone is an opioid antagonist shown to reduce the occurrence of addictive behaviours such as eating, smoking and drinking excessively. in addition to curbing drug use it has recently been used in flavor avoidance studies.
References Mannelli, P. et al.: Drug Alc. Dep. 138, 83 (2014); Rotella, F. et al.: 128, 133 (2014);

• Brand: TRC

Chemical properties

• Molecular weight: 341.40
• Formula: C₂₀H₂₃NO₄
• Color/Form: White To Light Beige
• InChI: InChI=1S/C20H23NO4/c22-13-4-3-12-9-15-20(24)6-5-14(23)18-19(20,16(12)17(13)25-18)7-8-21(15)10-11-1-2-11/h3-4,11,15,18,22,24H,1-2,5-10H2/t15-,18+,19+,20-/m1/s1
• InChI key: InChIKey=DQCKKXVULJGBQN-XFWGSAIBSA-N
• SMILES: O=C1CC[C@@]2(O)[C@H]3Cc4ccc(O)c5c4[C@@]2(CCN3CC2CC2)[C@H]1O5