Product Information
Name:Necrosulfonamide
Controlled Product
Synonyms:
- N-[4-[[(3-Methoxypyrazinyl)amino]sulfonyl]phenyl]-3-(5-nitro-2-thienyl)-2-propenamide
- (E)-N-[4-[N-(3-methoxypyrazin-2-yl)sulfamoyl]phenyl]-3-(5-nitrothiophene-2-yl)acrylamide
Brand:TRC
Description:Applications Necrosulfonamide specifically blocks necrosis downstream of receptor-interacting serine-threonine kinase 3 (RIP3) activation. RIP3 is a key signalling molecule in the programmed necrosis (necroptosis) pathway.References Sun, L. et al.: Cell, 148, 213 (2012);
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:461.47
Formula:C18H15N5O6S2
Color/Form:Neat
InChI:InChI=1S/C18H15N5O6S2/c1-29-18-17(19-10-11-20-18)22-31(27,28)14-6-2-12(3-7-14)21-15(24)8-4-13-5-9-16(30-13)23(25)26/h2-11H,1H3,(H,19,22)(H,21,24)/b8-4+
SMILES:COc1nccnc1NS(=O)(=O)c1ccc(NC(=O)/C=C/c2ccc([N+](=O)[O-])s2)cc1
Technical inquiry about: Necrosulfonamide
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