Nicergoline-d3

CAS: 27848-84-6

Ref. TR-N394552

Product Information

• Name: Nicergoline-d3
• Synonyms: [(6aR,9R,10aS)-10a-methoxy-7-methyl-4-(trideuteriomethyl)-6a,8,9,10-tetrahydro-6H-indolo[4,3-fg]quinolin-9-yl]methyl 5-bromopyridine-3-carboxylate, (+)-10-Methoxy-1,6-dimethylergoline-8-beta-methanol 5-bromonicotinate, (10-Methoxy-1,6-Dimethylergolin-8-Yl)Methyl 5-Bromopyridine-3-Carboxylate, (8β)-10-Methoxy-1,6-dimethylergoline-8-methanol-5-bromo-3-pyridinecarboxylate ester, 1,6-Dimethyl-8β-(5-bromonicotinoyloxymethyl)-10α-methoxyergoline, 1-Methyl-lumilysergol 8-(5-bromonicotinate) 10-methyl ether, 10-Methoxy-1,6-dimethyl-ergolin-8-beta-methanol-(5-bromnicotinat), 10-Methoxy-1,6-dimethyl-ergolin-8-beta-methanol-(5-bromnicotinat) [German], 10-Methoxy-1,6-dimethylergoline-8-methanol 5-bromo-3-pyrindinecarboxylate (ester), 10-Methoxy-1,6-dimethylergoline-8beta-methanol 5-bromonicotinate, 10-Methoxy-1,6-dimethylergoline-8beta-methanol 5-bromonicotinate (ester), 8-beta-((5-Bromonicotinoyloxy)methyl)-1,6-dimethyl-10-alpha-methoxyergoline, Brn 4828393, Cergodum, Circo-Maren, Dilasenil, Duracebrol, Ergobel, Ergoline-8-beta-methanol, 10-methoxy-1,6-dimethyl-, 5-bromo-3-pyridinecarboxylate (ester), Ergoline-8-beta-methanol, 10-methoxy-1,6-dimethyl-, 5-bromonicotinate (ester), Ergoline-8-methanol, 10-methoxy-1,6-dimethyl-, (8beta)-, 5-bromo-3-pyridinecarboxylate (ester), Ergoline-8-methanol, 10-methoxy-1,6-dimethyl-, 5-bromo-3-pyridinecarboxylate (ester), (8beta)-, Ergoline-8-methanol, 10-methoxy-1,6-dimethyl-, 5-bromo-3-pyridinecarboxylate (ester), (8β)-, Ergoline-8-methanol, 10-methoxy-1,6-dimethyl-, 8-(5-bromo-3-pyridinecarboxylate), (8β)-, Ergoline-8beta-methanol, 10-methoxy-1,6-dimethyl-, 5-bromonicotinate (ester) (8CI), Ergoline-8β-methanol, 10-methoxy-1,6-dimethyl-, 5-bromonicotinate (ester), Ergotop, Fi 6714, Indolo[4,3-fg]quinoline, ergoline-8-methanol deriv., MNE, Memoq, Nicergolent, Nicergolin, Nicergolin [German], Nicergolina, Nicergolina [DCIT], Nicergoline [USAN:INN:BAN:JAN], Nicergolinum, Nicergolinum [INN-Latin], Nicotergoline, Nicotinic acid, 5-bromo-, (10-methoxy-1,6-dimethylergolin-8β-yl)methyl ester, Nimergoline, Nimergoline base, Nsc 150531, Rp 19651, Sermion, Ta 079, Unii-Jcv8365Fwn, Vasospan, [(8Beta)-10-Methoxy-1,6-Dimethylergolin-6-Ium-8-Yl]Methyl 5-Bromopyridine-3-Carboxylate, [(8Beta)-10-Methoxy-1,6-Dimethylergolin-8-Yl]Methyl 5-Bromopyridine-3-Carboxylate
• CAS: 27848-84-6

Description

Applications Nicergoline-d3 is the labeled analogue of Nicergoline(N394550), a drug used for age-dependent cognitive impairment such as Alzheimers disease and other types of dementia.
References Caraci, F., et. al.: Brain Res., 1047, 30 (2005); Mizuno, T., et. al.: Brain Res., 1066, 78 (2005)

• Brand: TRC

Chemical properties

• Molecular weight: 487.404
• Formula: C₂₄H₂₃D₃BrN₃O₃
• Color/Form: Neat
• InChI: InChI=1S/C24H26BrN3O3/c1-27-13-17-8-21-24(30-3,19-5-4-6-20(27)22(17)19)9-15(12-28(21)2)14-31-23(29)16-7-18(25)11-26-10-16/h4-7,10-11,13,15,21H,8-9,12,14H2,1-3H3/t15-,21-,24+/m1/s1/i1D3
• InChI key: InChIKey=YSEXMKHXIOCEJA-VHTLWHJUSA-N
• SMILES: [2H]C([2H])([2H])n1cc2c3c(cccc31)[C@@]1(OC)C[C@@H](COC(=O)c3cncc(Br)c3)CN(C)[C@@H]1C2