N-Nitroso Lorazepam

CAS: 846-49-1

Ref. TR-N469850

Product Information

• Name: N-Nitroso Lorazepam
• Synonyms: 7-Chloro-5-(2-chlorophenyl)-3-hydroxy-1-nitroso-1H-benzo[e][1,4]diazepin-2(3H)-one, (.+-.)-Lorazepam, (RS)-Lorazepam, 2H-1,4-Benzodiazepin-2-one, 7-chloro-5-(o-chlorophenyl)-1,3-dihydro-3-hydroxy-, 7-Chloro-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4-benzodiazepin-2-one, 7-Chloro-5-(2-chlorophenyl)-3-hydroxy-1H-1,4-benzodiazepin-2(3H)-one, 7-Chloro-5-(o-chlorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4-benzodiazepin-2-one, Almazine, Anxiedin, Anxira, Anzepam, Aplacasse, Aplacassee, Apo-Lorazepam, Aripax, Ativan, Azurogen, Bonatranquan, Bonton, Control, Delormetazepam, Demethyllormetazepam, Duralozam, Efasedan, Emotival, Equitam, Kalmalin, Larpose, Laubeel, Lopam, Lorabenz, Loram, Lorans, Lorapam, Lorat, Lorax, Lorazem, Lorazene, Lorazep, Lorazin, Lorazon, Lorenin, Loridem, Lorivan, Lorsedal, Lorsilan, Lorzem, Lozepam, Merlit, NIC, Nervistop L, Norlormetazepam, Novhepar, Novo-lorazem, Nsc 289758, Orfidal, Pro Dorm, Psicopax, Punktyl, Quait, Renaquil, Reposepan, Rocosgen, Securit, Sedatival, Sedazin, Sedizepan, Sidenar, Silence, Sinestron, Somagerol, Stapam, Tavor, Tavor Expidet, Temesta, Titus, Tranqipam, Trapax, Trapex, Upan, Wintin, Wy 4036, Wypax, o-Chlorooxazepam, o-Chloroxazepam

Description

Applications N-Nitroso Lorazepam is an impurity of Lorazepam (L469850), which is an anxiolytic compound that potentiates GABAergic synaptic transmission by binding at the benzodiazepine site on the GABAA receptor.1,2 This product is intended for forensic and research applications. Lorazepam acts as ananticonvulsant.
References Rutgers, G., et al.: Anal. Profiles Drug Subs., 9, 397 (1980), Korkmaz, S., et al.: Eur. Neuropsychopharmacol., 8, 175 (1998), D’Onofrio, G., et al.: N. Engl. J. Med., 340, 915 (1999),

• Brand: TRC

Chemical properties

• Molecular weight: 350.16
• Formula: C₁₅H₉Cl₂N₃O₃
• Color/Form: Neat
• InChI: InChI=1S/C15H9Cl2N3O3/c16-8-5-6-12-10(7-8)13(9-3-1-2-4-11(9)17)18-14(21)15(22)20(12)19-23/h1-7,14,21H
• InChI key: InChIKey=FNTIYSQGSPWJJG-UHFFFAOYSA-N
• SMILES: O=NN1C(=O)C(O)N=C(c2ccccc2Cl)c2cc(Cl)ccc21