N-Nitroso Lorazepam

CAS: 846-49-1

Ref. TR-N469850

Product Information

• Name: N-Nitroso Lorazepam
• Synonyms: 7-Chloro-5-(2-chlorophenyl)-3-hydroxy-1-nitroso-1H-benzo[e][1,4]diazepin-2(3H)-one
• Brand: TRC
• Description: Applications N-Nitroso Lorazepam is an impurity of Lorazepam (L469850), which is an anxiolytic compound that potentiates GABAergic synaptic transmission by binding at the benzodiazepine site on the GABAA receptor.1,2 This product is intended for forensic and research applications. Lorazepam acts as ananticonvulsant.References Rutgers, G., et al.: Anal. Profiles Drug Subs., 9, 397 (1980), Korkmaz, S., et al.: Eur. Neuropsychopharmacol., 8, 175 (1998), D’Onofrio, G., et al.: N. Engl. J. Med., 340, 915 (1999),

Chemical properties

• Molecular weight: 350.16
• Formula: C₁₅H₉Cl₂N₃O₃
• Color/Form: Neat
• InChI: InChI=1S/C15H9Cl2N3O3/c16-8-5-6-12-10(7-8)13(9-3-1-2-4-11(9)17)18-14(21)15(22)20(12)19-23/h1-7,14,21H
• InChI key: InChIKey=FNTIYSQGSPWJJG-UHFFFAOYSA-N
• SMILES: O=NN1C(=O)C(O)N=C(c2ccccc2Cl)c2cc(Cl)ccc21