Estimated delivery in United States, on Monday 16 Dec 2024
Product Information
Name:
Niraparib Tosylate
Synonyms:
- (3S)-3-[4-[7-(Aminocarbonyl)-2H-indazol-2-yl]phenyl]piperidine Tosylate
- MK-4827 Tosylate
Description:
Applications Niraparib is a novel oral poly(ADP-ribose)polymerase (PARP) inhibitor efficacious in BRCA-1 and -2 mutant tumors.
References Jones, P., et al.: J. Med. Chem., 52, 7170 (2009); Giannini, G., et al.: Bioorg. Med. Chem. Lett., 24, 462 (2014)
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
320.39 + (172.20)
Formula:
C19H20N4O·C7H8O3S
Color/Form:
Off-White To Light Yellow
InChI:
InChI=1S/C19H20N4O.C7H8O3S/c20-19(24)17-5-1-3-15-12-23(22-18(15)17)16-8-6-13(7-9-16)14-4-2-10-21-11-14;1-6-2-4-7(5-3-6)11(8,9)10/h1,3,5-9,12,14,21H,2,4,10-11H2,(H2,20,24);2-5H,1H3,(H,8,9,10)/t14-;/m1./s1
InChI key:
InChIKey=LCPFHXWLJMNKNC-PFEQFJNWSA-N
SMILES:
Cc1ccc(S(=O)(=O)O)cc1.NC(=O)c1cccc2cn(-c3ccc([C@@H]4CCCNC4)cc3)nc12
MDL:
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Technical inquiry about: TR-N481405 Niraparib Tosylate
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