Product Information
- N-Nitrosonornicotine
- 1-Nitroso-2-(3-pyridyl)pyrrolidine
- 3-(1-Nitroso-2-pyrrolidinyl)pyridine
- Pyridine, 3-(1-nitroso-2-pyrrolidinyl)-
Applications N'-Nitrosonornicotine (NNN) is a tobacco alkaloid known as esophageal carcinogen. NNN is the cause of esophageal and oral cavity cancer in smokers and snuff dippers. The studies showed that the carcinogenicity of (S)-NNN, the predominant enantiomer in tobacco products, may be greater than that of (R)-NNN or racemic NNN.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Anto, R., et al.: Carcinogenesis, 23, 1511 (2002), Pfeifer, G., et al.: Oncogene, 21, 7435 (2002), Shishodia, S., et al.: Cancer Res., 64, 5004 (2004), Jin, Z., et al.: J. Biol. Chem., 279, 23837 (2004),
Chemical properties
Technical inquiry about: TR-N535000 rac-N’-Nitroso Nornicotine
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