Product Information
Name:ONX 0914
Controlled Product
Synonyms:
- PR 957
- N-[2-(4-Morpholinyl)acetyl]-L-alanyl-O-methyl-N-[(1S)-2-[(2R)-2-methyl-2-oxiranyl]-2-oxo-1-(phenylmethyl)ethyl]-L-tyrosinamide
Brand:TRC
Description:Applications ONX 0914 is a proteosome inhibitor known for treatming malignancies and more recently, effacaciously inducing apoptosis for cancers. Used in the treatment of autoimmune diseases.References Mulder, A. et a.L Transplantation, 95, 1331 (2013); Screen, M. et al.: J. Biol. Chem., 285, 40125 (2010);
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:580.67
Formula:C31H40N4O7
Color/Form:Neat
InChI:InChI=1S/C31H40N4O7/c1-21(32-27(36)19-35-13-15-41-16-14-35)29(38)34-26(18-23-9-11-24(40-3)12-10-23)30(39)33-25(28(37)31(2)20-42-31)17-22-7-5-4-6-8-22/h4-12,21,25-26H,13-20H2,1-3H3,(H,32,36)(H,33,39)(H,34,38)/t21-,25-,26-,31-/m0/s1
InChI key:InChIKey=WQAVPPWWLLVGFK-VTNASVEKSA-N
SMILES:COc1ccc(C[C@H](NC(=O)[C@H](C)NC(=O)CN2CCOCC2)C(=O)N[C@@H](Cc2ccccc2)C(=O)[C@@]2(C)CO2)cc1
Technical inquiry about: ONX 0914
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