(E)-2-Oxo-3-(2-phenylhydrazono)butanoic Acid

CAS: 1005763-87-0

Ref. TR-O992555

Product Information

• Name: (E)-2-Oxo-3-(2-phenylhydrazono)butanoic Acid
• Synonyms: 2,3-dioxo-3-(phenylhydrazone)butyric Acid, Edaravone Impurity
• CAS: 1005763-87-0

Description

Applications (E)-2-Oxo-3-(2-phenylhydrazono)butanoic Acid is an impurity of Edaravone (E335000), which inhibits the disease activity in rheumatoid arthritis. Edaravone can also significantly enhance IR flap viability and protect flap vessels, which is related to scavenging oxygen free radicals, reducing the consumption of SOD, reducing the extent of lipid peroxidation and inflammation, and protecting functional structure of vessels in the early stages of reperfusion
References Watanabe, K., et. al.: Nihon Yukagakkaishi, 46, 797 (1997);Kawai, H., et. al.: J. Pharmacol. Exp. Ther., 281, 921 (1997);Yamamoto, Y., et. al.: Redox Rep., 2, 333 (1996);

• Brand: TRC

Chemical properties

• Molecular weight: 206.198
• Formula: C₁₀H₁₀N₂O₃
• InChI: InChI=1S/C10H10N2O3/c1-7(9(13)10(14)15)11-12-8-5-3-2-4-6-8/h2-6,12H,1H3,(H,14,15)/b11-7+