CAS 1005763-87-0

Formula: C10H10N2O3

InChI: InChI=1S/C10H10N2O3/c1-7(9(13)10(14)15)11-12-8-5-3-2-4-6-8/h2-6,12H,1H3,(H,14,15)/b11-7+

InChI key: VXUYGKHNIJIEHO-YRNVUSSQSA-N

SMILES: C/C(=N\NC1=CC=CC=C1)/C(=O)C(=O)O

(E)-2-Oxo-3-(2-phenylhydrazono)butanoic Acid

Controlled Product

CAS: 1005763-87-0

Applications (E)-2-Oxo-3-(2-phenylhydrazono)butanoic Acid is an impurity of Edaravone (E335000), which inhibits the disease activity in rheumatoid arthritis. Edaravone can also significantly enhance IR flap viability and protect flap vessels, which is related to scavenging oxygen free radicals, reducing the consumption of SOD, reducing the extent of lipid peroxidation and inflammation, and protecting functional structure of vessels in the early stages of reperfusion
References Watanabe, K., et. al.: Nihon Yukagakkaishi, 46, 797 (1997);Kawai, H., et. al.: J. Pharmacol. Exp. Ther., 281, 921 (1997);Yamamoto, Y., et. al.: Redox Rep., 2, 333 (1996);

Formula: C₁₀H₁₀N₂O₃

Color and Shape: Neat

Molecular weight: 206.198

Ref: TR-O992555