Perphenazine

CAS: 58-39-9

Ref. TR-P291100

Product Information

• Name: Perphenazine
• Synonyms: Fluphenazine Dihydrochloride Imp. E (EP), Fluphenazine Imp. E (EP), 1-Piperazineethanol, 4-[3-(2-chlorophenothiazin-10-yl)propyl]- (8CI), 4-[3-(2-Chloro-10H-phenothiazin-10-yl)propyl]-1-piperazineethanol, 1-(2-Hydroxyethyl)-4-[3-(2-chloro-10-phenothiazinyl)propyl]piperazine, 2-Chloro-10-3-[1-(2-hydroxyethyl)-4-piperazinyl] propyl phenothiazine, 2-Chloro-10-[3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl]phenothiazine, Chloriprozine, Chlorperphenazine, Decentan, Emesinal, Etaperazin, Etaperazine, Ethaperazine, Fentazin, Fentazin syrup, Fentazine duolets, Mutabom, NSC 150866, PZC, PZC (tranquilizer), Perfenazine, Perfenil, Perphenan, Perphenazin, Sch 3940, Thilatazin, Tranquisan, Trifaron, Trilafon, Trilifan, Triphenot, gamma-[4-(beta-Hydroxyethyl)piperazin-1-yl]propyl-2-chlorophenothiazine, Fluphenazine Dihydrochloride Impurity E, Fluphenazine Impurity E, 1-Piperazineethanol, 4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-, 1-Piperazineethanol, 4-[3-(2-chlorophenothiazin-10-yl)propyl]-, 2-(4-(3-(2-Chlorophenothiazin-10-Yl)Propyl)Piperazin-1-Yl)Ethanol, 2-Chloro-10-[3'-(4''-(2'''-hydroxyethyl)piperazinyl)propyl]-phenothiazine, 2-[4-[3-(2-Chloro-10H-phenothiazin-10-yl)propyl]piperazin-1-yl]ethan-1-ol, 2-[4-[3-(2-Chloro-phenothiazin-10-yl)-propyl]-piperazin-1-yl]-ethanol, 4-[3-(2-Chloro-10H-phenothiazin-10-yl)propyl]-1-piperazinethanol, Nsc 150866, Perfenazina, γ-[4-(β-Hydroxyethyl)piperazin-1-yl]propyl-2-chlorophenothiazine

Description

Applications D2 dopamine receptor antagonist; α-adrenergic receptor antagonist and σ-receptor agonist; phenothiazine antipsychotic. Inhibits glutamate dehydrogenase in vitro. Antipsychotic.
References Gaertner, H.J., et al.: Drug Metab. Dispos., 3, 437 (1975), O Brien, S., et al.: J. Med. Chem., 48, 1287 (2005), Briggs, K., et al.: Toxicology, 231, 113 (2007), Toga, T., et al.: J. Pharmacol. Sci., 105, 207 (2007),

• Brand: TRC

Chemical properties

• Molecular weight: 403.97
• Formula: C₂₁H₂₆ClN₃OS
• Color/Form: Neat
• InChI: InChI=1S/C21H26ClN3OS/c22-17-6-7-21-19(16-17)25(18-4-1-2-5-20(18)27-21)9-3-8-23-10-12-24(13-11-23)14-15-26/h1-2,4-7,16,26H,3,8-15H2
• InChI key: InChIKey=RGCVKNLCSQQDEP-UHFFFAOYSA-N
• SMILES: OCCN1CCN(CCCN2c3ccccc3Sc3ccc(Cl)cc32)CC1