Piribedil

CAS: 3605-01-4

Ref. TR-P508750

Product Information

• Name: Piribedil
• Synonyms: Pyrimidine, 2-[4-(1,3-benzodioxol-5-ylmethyl)-1-piperazinyl]- (9CI, ACI), 2-[4-(1,3-Benzodioxol-5-ylmethyl)-1-piperazinyl]pyrimidine (ACI), Pyrimidine, 2-(4-piperonyl-1-piperazinyl)- (7CI, 8CI), 1-(2-Pyrimidyl)-4-(3,4-methylenedioxybenzyl)piperazine, 1-(2-Pyrimidyl)-4-piperonylpiperazine, 2-(4-(Benzo[d][1,3]dioxol-5-ylmethyl)piperazin-1-yl)pyrimidine, 4-[3,4-(Methylenedioxy)benzyl]-1-(2-pyrimidinyl)piperazine, ET 495, EU 4200, Pronoran, Trivastal, Trivastan, 2-[4-(1,3-Benzodioxol-5-Ylmethyl)Piperazin-1-Yl]Pyrimidine, 2-[4-(1,3-Benzodioxol-5-Ylmethyl)Piperazin-1-Yl]Pyrimidine Methanesulfonate (1:1), 2[4-(1,3-Benzodioxol-5-Ylmethyl)-1-Piperazinyl-]Pyrimidine, Et 495, Eu 4200, Piribendyl, Pyrimidine, 2-(4-piperonyl-1-piperazinyl)-, Pyrimidine, 2-[4-(1,3-benzodioxol-5-ylmethyl)-1-piperazinyl]-

Description

Applications Piribedil is an antiparkisonian agent that acts as a dopamine agonist. Piribedil also displays α2-adrenergic antagonist properties. Piribedil has also been shown to counteract age-related memory impairment by improving memory and attention as well as increasing the velocity of psychomotor reactions and lability of nervous processes.
References Millan, M.J. et al.: J. Pharmacol. Exp. Therap., 297, 876 (2001); Gobert, A. et al.: J. Pharmacol. Exp. Therap., 305, 338 (2003); Bochkarev, V.K. et al.: Zh. Nevrol. Psikhiatr. Im. S.S. Korsakova, 105, 46 (2005);

• Brand: TRC

Chemical properties

• Molecular weight: 298.34
• Formula: C₁₆H₁₈N₄O₂
• Color/Form: White
• InChI: InChI=1S/C16H18N4O2/c1-4-17-16(18-5-1)20-8-6-19(7-9-20)11-13-2-3-14-15(10-13)22-12-21-14/h1-5,10H,6-9,11-12H2
• InChI key: InChIKey=OQDPVLVUJFGPGQ-UHFFFAOYSA-N
• SMILES: c1cnc(N2CCN(Cc3ccc4c(c3)OCO4)CC2)nc1