L-Proline-d3-N-Fmoc

CAS: 71989-31-6

Ref. TR-P756007

Product Information

• Name: L-Proline-d3-N-Fmoc
• Synonyms: (2S)-1,2-Pyrrolidinedicarboxylic acid, 1-(9H-fluoren-9-ylmethyl) ester, (S)-1,2-Pyrrolidinedicarboxylic acid, 1-(9H-fluoren-9-ylmethyl) ester, (S)-N-(9-Fluorenylmethoxycarbonyl)proline, Fluorenylmethoxycarbonylproline, Fmoc-L-Pro-OH, Fmoc-L-proline, Fmoc-Pro-OH, N-(9-Fluorenylmethoxycarbonyl)-L-proline, N-(9-Fluorenylmethoxycarbonyl)proline, N-FMOC-L-proline, NSC 334294, (2S)-1-[(9H-Fluoren-9-ylmethoxy)carbonyl]pyrrolidine-2-carboxylic acid, (2S)-1-[[(9H-Fluoren-9-yl)methoxy]carbonyl]pyrrolidine-2-carboxylic acid, (S)-hidrogenopirrolidina-1,2-dicarboxilato de 1-(9H-fluoren-9-ilmetilo), (S)-hydrogenopyrrolidine-1,2-dicarboxylate de 1-(9H-fluorene-9-ylmethyle), 1,2-Pyrrolidinedicarboxylic acid, 1-(9H-fluoren-9-ylmethyl) ester, (S)-, 1-(9H-fluoren-9-ylmethyl) hydrogen (S)-pyrrolidine-1,2-dicarboxylate, 1-(9H-fluoren-9-ylmethyl)-(S)-hydrogenpyrrolidin-1,2-dicarboxylat, Fmoc-<span class="text-smallcaps">L</span>-Pro-OH, Fmoc-<span class="text-smallcaps">L</span>-proline, N-(9-Fluorenylmethoxycarbonyl)-<span class="text-smallcaps">L</span>-proline, N-FMOC-<span class="text-smallcaps">L</span>-proline, Nsc 334294

Description

Applications L-Proline-d3-N-Fmoc was used to prepare potent bombesin-like peptides for GRP-receptor targeting of tumors. It was also used to synthesize tetrapeptide aldehyde inhibitors of dengue virus NS3 protease.
References Nock, B., et al.: J. Med. Chem., 48, 100 (2005); Yin, Z., et al.: Bioorg. Med. Chem. Lett., 16, 40 (2006)

• Brand: TRC

Chemical properties

• Molecular weight: 340.39
• Formula: C₂₀H₁₆D₃NO₄
• Color/Form: Neat
• InChI: InChI=1S/C20H19NO4/c22-19(23)18-10-5-11-21(18)20(24)25-12-17-15-8-3-1-6-13(15)14-7-2-4-9-16(14)17/h1-4,6-9,17-18H,5,10-12H2,(H,22,23)/t18-/m0/s1/i11D2,18D
• InChI key: InChIKey=ZPGDWQNBZYOZTI-XALRRENSSA-N
• SMILES: [2H]C1([2H])CC[C@@]([2H])(C(=O)O)N1C(=O)OCC1c2ccccc2-c2ccccc21