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β-Pseudouridine

CAS:

Ref. TR-P839605

10mg
105.00€
25mg
193.00€
2500µg
97.00€
β-Pseudouridine
TRC

Product Information

Name:β-Pseudouridine
Controlled Product
Synonyms:
  • 5-β-D-Ribofuranosyl-2,4(1H,3H)-Pyrimidinedione
  • 5-(β-D-Ribofuranosyl)uracil
  • 5-Ribosyluracil
  • NSC 162405
  • Pseudouridine C
  • β-D-Pseudouridine
  • Pseudouridine
  • ψ-Uridine
Brand:TRC
Description:Applications An isomer of the nucleoside uridine found in all species and in many classes of RNA except mRNA. It is formed by enzymes called Ψ synthases, which post-transcriptionally isomerize specific uridine residues in RNA in a process termed pseudouridylation. Studies suggest that β-Pseudouridine reduces radiation-induced chromosome aberrations in human lymphocytes.References Ferré-D'Amaré A.R. et al.: Curr. Opin. Struct. Biol., 13, 49 (2003); Hamma, T. et al.: Chem. Biol., 13, 1125 (2006); Liang, X.H. et al.: RNA, 8, 237 (2002); Monobe, M. et al.: Mut. Res. Gen. Toxicol. Env. Mutagen., 538, 93 (2003);
Notice:Our products are intended for lab use only. For any other use, please contact us.

Chemical properties

Molecular weight:244.20
Formula:C9H12N2O6
Color/Form:Neat
InChI:InChI=1S/C9H12N2O6/c12-2-4-5(13)6(14)7(17-4)3-1-10-9(16)11-8(3)15/h1,4-7,12-14H,2H2,(H2,10,11,15,16)/t4-,5-,6-,7+/m1/s1
InChI key:InChIKey=PTJWIQPHWPFNBW-GBNDHIKLSA-N
SMILES:O=c1[nH]cc([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)[nH]1

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