L-Pyroglutamic Acid

CAS: 98-79-3

Ref. TR-P997480

Product Information

• Name: L-Pyroglutamic Acid
• Synonyms: 5-Oxo-L-proline, Proline, 5-oxo-, L- (8CI), (-)-2-Pyrrolidone-5-carboxylic acid, (-)-Pyroglutamic acid, (2S)-5-Oxopyrrolidine-2-carboxylic acid, (5S)-2-Oxopyrrolidine-5-carboxylic acid, (S)-(-)-2-Pyrrolidone-5-carboxylic acid, (S)-2-Pyrrolidone-5-carboxylic acid, (S)-5-Oxo-1H-pyrrolidine-2-carboxylic acid, (S)-5-Oxo-2-pyrrolidinecarboxylic acid, (S)-5-Oxoproline, (S)-Pyroglutamic acid, 2-L-Pyrrolidone-5-carboxylic acid, 2-Oxopyrrolidine-5(S)-carboxylic acid, 2-Pyrrolidinone-5-carboxylic acid, 5-Carboxy-2-pyrrolidinone, 5-Oxoproline, 5-Pyrrolidinone-2-carboxylic acid, Ajidew A 100, Glutimic acid, Glutiminic acid, L-2-Pyrrolidone-5-carboxylic acid, L-5-Carboxy-2-pyrrolidinone, L-5-Oxo-2-pyrrolidinecarboxylic acid, L-5-Oxoproline, L-Glutimic acid, L-Glutiminic acid, L-Pyrrolidinonecarboxylic acid, L-Pyrrolidonecarboxylic acid, NSC 143034, Oxoproline, Oxopyrrolidinecarboxylic acid, PCA, PCA 50, Pidolic acid, Pidolidone, Pyroglutamic acid, Pyrrolidinonecarboxylic acid, Pyrrolidone-5-carboxylic acid, Pyrrolidonecarboxylic acid, (S)-(-)-gamma-Butyrolactam-gamma-carboxylic acid, L-Glutamic acid, gamma-lactam, (2S)-5-oxopyrrolidine-2-carboxylate, (S)-(-)-2-Pyrrolidinone-5-carboxylic acid, (S)-(-)-γ-Butyrolactam-γ-carboxylic acid, 2-<span class="text-smallcaps">L</span>-Pyrrolidone-5-carboxylic acid, 2-Pyrrolidon-5-carboxylic acid, 2-Pyrrolidone Carboxylic Acid, 5-Oxo-<span class="text-smallcaps">L</span>-proline, 5-Oxopyrrolidine-2-carboxylic acid, 5-Pyrrolidone-2-carboxylic acid, <span class="text-smallcaps">L</span>-(-)-Pyroglutamic acid, <span class="text-smallcaps">L</span>-2-Pyrrolidone-5-carboxylic acid, <span class="text-smallcaps">L</span>-5-Carboxy-2-pyrrolidinone, <span class="text-smallcaps">L</span>-5-Oxo-2-pyrrolidinecarboxylic acid, <span class="text-smallcaps">L</span>-5-Oxoproline, <span class="text-smallcaps">L</span>-Glutamic acid, γ-lactam, <span class="text-smallcaps">L</span>-Glutimic acid, <span class="text-smallcaps">L</span>-Glutiminic acid, <span class="text-smallcaps">L</span>-Proline, 5-oxo-, <span class="text-smallcaps">L</span>-Pyroglutamine, <span class="text-smallcaps">L</span>-Pyrrolidinonecarboxylic acid, <span class="text-smallcaps">L</span>-Pyrrolidonecarboxylic acid, Acide pidolique, Acido Pidolico, Glutiminic Acid, H-Pyr-OH, L-5-Pyrrolidone-2-carboxylic acid, L-Glutamic acid, γ-lactam, L-Proline, 5-oxo-, L-Pyroglutamic acid, L-Pyrpglutamic Acid, L-pyro glutamic acid, Nsc 143034, Pca 50, Pidolic Acid, Pidolinsaure, Proline, 5-oxo-, <span class="text-smallcaps">L</span>-, Proline, 5-oxo-, L-, Pyr-OH, Pyroglutamic Acid, Pyroglutamicacid, Pyroglutamine, Pyrrolid-2-One-5-Carboxylic Acid, Pyrrolidonecarboxylic Acid, Take Off Booster, Vls 3000-01

Description

Applications L-Pyroglutamic acid is an amino acid that is used in the synthesis of peptides. It has also been observed to convert when placed at the N-terminus in vivo to create IgG2 antibodies.
References Wirths, O. et al.: J. Biol. Chem., 53, 41517 (2010); Liu, Y.D. et al.: J. Biol. Chem., 286, 11211 (2011);

• Brand: TRC

Chemical properties

• Molecular weight: 129.11
• Formula: C₅H₇NO₃
• Color/Form: White To Off-White
• InChI: InChI=1S/C5H7NO3/c7-4-2-1-3(6-4)5(8)9/h3H,1-2H2,(H,6,7)(H,8,9)/t3-/m0/s1