9-cis-Retinoic Acid

CAS: 5300-03-8

Ref. TR-R245000

Product Information

• Name: 9-cis-Retinoic Acid
• Synonyms: Retinoic acid, cis-9,trans-13- (8CI), 9(Z)-Retinoic acid, 9-cis-Tretinoin, AGN 192013, ALRT 1057, Alitretinoin, LG 100057, LGD 100057, LGD 1057, NSC 659772, Panretin, Panretyn, Panrexin, Toctino, BAL0004079-000, code for free acid, BAL4079, 9-(Z) Retinoic Acid, R0004079-000, CRA-Alitretinoin, INN Alitretinoin, 9-Cis-Tretinoin, Agn 192013, Alrt 1057, Lg 100057, Lgd 100057, Lgd 1057, Retinoic acid, 9-cis-, Retinoic acid, cis-9,trans-13-, 9-cis-Retinoic acid, 9-cis-Retinoic acid

Description

Stability Light Sensitive, Temperature Sensitive
Applications An endogenous retinoic acid isomer, which is capable of binding to both retinoic acid receptors (RAR) and retinoid X receptors (RXR). A biologically active ligand for members of the RAR and RXR subfamilies, implying that it may play a critical role in regulating retinoid-responsive pathways.
References Heyman, R.A., et al.: Cell, 68, 397 (1992), Levin, A.A., et al.: Nature, 355, 359 (1992), Allenby, G., et al.: Proc. Natl. Acad. Sci. U.S.A., 90, 30 (1993)

• Brand: TRC

Chemical properties

• Molecular weight: 300.44
• Formula: C₂₀H₂₈O₂
• Color/Form: Light Yellow
• InChI: InChI=1S/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8-,16-14+
• InChI key: InChIKey=SHGAZHPCJJPHSC-ZVCIMWCZSA-N
• SMILES: CC1=C(/C=C/C(C)=C\C=C\C(C)=C\C(=O)O)C(C)(C)CCC1