Product Information
Name:Retorphan
Controlled Product
Synonyms:
- N-[(2R)-2-[(Acetylthio)methyl]-1-oxo-3-phenylpropyl]glycine Phenylmethyl Ester
- Dexecadotril
Brand:TRC
Description:Applications Retorphan is a powerful and selective inhibitors of neprilysin and is being developed as a therapeutic agent. Retorphan behave as the prodrug of the enantiomers of Thiorphan (T369500).References Monteil, T., et al.: Mini. Rev. Med. Chem., 2, 209 (2002); Roques, B.P., et al.: Nature, 288, 286 (1980); Tiraboschi, G., et al.: Protein Engineering, 12, 2, 141 (1999)
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Chemical properties
Molecular weight:385.48
Formula:C21H23NO4S
Color/Form:Neat
InChI:InChI=1S/C21H23NO4S/c1-16(23)27-15-19(12-17-8-4-2-5-9-17)21(25)22-13-20(24)26-14-18-10-6-3-7-11-18/h2-11,19H,12-15H2,1H3,(H,22,25)/t19-/m0/s1
InChI key:InChIKey=RQUVSNGNEJMOBE-VTFQDDHLSA-N
SMILES:C=CCOc1nc2c(=O)[nH]c(N)nc2n1[C@@H]1O[C@H](CO)C(O)C1O
Technical inquiry about: Retorphan
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