Estimated delivery in United States, on Tuesday 18 Feb 2025
Product Information
Name:
Retorphan
Controlled Product
Synonyms:
- benzyl 2-[[(2R)-2-(acetylsulfanylmethyl)-3-phenylpropanoyl]amino]acetate
- Dexecadotril [INN]
- (+)-N-((R)-alpha-(Mercaptomethyl)hydrocinnamoyl)glycine, benzyl ester, acetate (ester)
- (R)-Acetorphan
- (R)-N-(2-((Acetylthio)methyl)-1-oxo-3-phenylpropyl)glycine phenylmethyl ester
- N-(2-Acetylthiomethyl-1-oxo-3-phenylpropyl)glycine-R(+)-benzyl ester
- Unii-5Ofi9D9892
- Glycine, N-(2-((acetylthio)methyl)-1-oxo-3-phenylpropyl)-, phenylmethyl ester, (R)-
- benzyl N-[(2R)-3-(acetylsulfanyl)-2-benzylpropanoyl]glycinate
Description:
Applications Retorphan is a powerful and selective inhibitors of neprilysin and is being developed as a therapeutic agent. Retorphan behave as the prodrug of the enantiomers of Thiorphan (T369500).
References Monteil, T., et al.: Mini. Rev. Med. Chem., 2, 209 (2002); Roques, B.P., et al.: Nature, 288, 286 (1980); Tiraboschi, G., et al.: Protein Engineering, 12, 2, 141 (1999)
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
385.48
Formula:
C21H23NO4S
Color/Form:
Neat
InChI:
InChI=1S/C21H23NO4S/c1-16(23)27-15-19(12-17-8-4-2-5-9-17)21(25)22-13-20(24)26-14-18-10-6-3-7-11-18/h2-11,19H,12-15H2,1H3,(H,22,25)/t19-/m0/s1
InChI key:
InChIKey=RQUVSNGNEJMOBE-VTFQDDHLSA-N
SMILES:
C=CCOc1nc2c(=O)[nH]c(N)nc2n1[C@@H]1O[C@H](CO)C(O)C1O
MDL:
Melting point:
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Density:
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EINECS:
Merck:
HS code:
Technical inquiry about: TR-R278500 Retorphan
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