Product Information
Name:RKI-1447
Controlled Product
Synonyms:
- 1-[(3-hydroxyphenyl)methyl]-3-(4-pyridin-4-yl-1,3-thiazol-2-yl)urea
Brand:TRC
Description:
Applications RKI-1447 is a potent and selective ROCK1 and ROCK2 inhibitor with significant anti-invasive and anti-tumor activies.
References Patel, R.A., et al.: Cancer Res., 72, 5025 (2012); Pireddu, R., et al.: Med. Chem. Comm., 3, 699 (2012)
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:326.37
Formula:C16H14N4O2S
Color/Form:Neat
InChI:InChI=1S/C16H14N4O2S/c21-13-3-1-2-11(8-13)9-18-15(22)20-16-19-14(10-23-16)12-4-6-17-7-5-12/h1-8,10,21H,9H2,(H2,18,19,20,22)
InChI key:InChIKey=GDVRVPIXWXOKQO-UHFFFAOYSA-N
SMILES:O=C(NCc1cccc(O)c1)Nc1nc(-c2ccncc2)cs1
Technical inquiry about: RKI-1447
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