Suramin (Sodium Salt)

CAS: 129-46-4

Ref. TR-S860000

Product Information

• Name: Suramin (Sodium Salt)
• Synonyms: Antrypol, Bayer 205, Germanin, Moranyl, Naganine, Suramine sodium, 8,8'-(Carbonylbis(imino-3,1-phenylenecarbonylimino(4-methyl-3,1-phenylene)carbonylimino))bis-1,3,5-naphthalenetrisulfonic acid hexasodium salt
• Brand: TRC

Description

Stability Hygroscopic
Applications Sodium salt of Suramin, a hepatitis C virus NS3 helicase inhibitor. Also used in the treatment of arthritis due to problematic collagen.
References Mukherjee, S. et al.: Nucl. Acids Res., 40, 8607 (2012); Sahu, D. et al.: Int. Immunopharmacol., 12, 288 (2012);

Chemical properties

• Molecular weight: 1429.17
• Formula: C₅₁H₃₄N₆O₂₃S₆·6Na
• Color/Form: Neat
• InChI: InChI=1S/C51H40N6O23S6.6Na/c1-25-9-11-29(49(60)54-37-13-15-41(83(69,70)71)35-21-33(81(63,64)65)23-43(45(35)37)85(75,76)77)19-39(25)56-47(58)27-5-3-7-31(17-27)52-51(62)53-32-8-4-6-28(18-32)48(59)57-40-20-30(12-10-26(40)2)50(61)55-38-14-16-42(84(72,73)74)36-22-34(82(66,67)68)24-44(46(36)38)86(78,79)80;;;;;;/h3-24H,1-2H3,(H,54,60)(H,55,61)(H,56,58)(H,57,59)(H2,52,53,62)(H,63,64,65)(H,66,67,68)(H,69,70,71)(H,72,73,74)(H,75,76,77)(H,78,79,80);;;;;;/q;6*+1/p-6
• InChI key: InChIKey=VAPNKLKDKUDFHK-UHFFFAOYSA-H
• SMILES: Cc1ccc(C(=O)Nc2ccc(S(=O)(=O)O[Na])c3cc(S(=O)(=O)O[Na])cc(S(=O)(=O)O[Na])c23)cc1NC(=O)c1cccc(NC(=O)Nc2cccc(C(=O)Nc3cc(C(=O)Nc4ccc(S(=O)(=O)O[Na])c5cc(S(=O)(=O)O[Na])cc(S(=O)(=O)O[Na])c45)ccc3C)c2)c1