Terfenadine

CAS: 50679-08-8

Ref. TR-T114500

Product Information

• Name: Terfenadine
• Synonyms: α-[4-(1,1-Dimethylethyl)phenyl]-4-(hydroxydiphenylmethyl)-1-piperidinebutanol, 1,2-Dipalmitoyl-sn-glycero-3-phospho-L-serine, sodium salt, 1-(4-Tert-Butylphenyl)-4-(4-(Hydroxydiphenylmethyl)Piperid-1-Yl)Butan-1-Ol, 1-(4-Tert-Butylphenyl)-4-{4-[Hydroxy(Diphenyl)Methyl]Piperidin-1-Yl}Butan-1-Ol, 1-Piperidinebutanol, α-[4-(1,1-dimethylethyl)phenyl]-4-(hydroxydiphenylmethyl)-, 1-[(4R)-4-(4-tert-butylphenyl)-4-hydroxybutyl]-4-[hydroxy(diphenyl)methyl]piperidinium, 1-[(4S)-4-(4-tert-butylphenyl)-4-hydroxybutyl]-4-[hydroxy(diphenyl)methyl]piperidinium, Allerplus, Cyater, DPPS, Na, Histadin, Histafen, Mdl 9918, Nebralin, Nsc 665802, Racemic terfenadine, Seldane, Teldane, Teldanex, Terdin, Terfenadin, Terfenadina, Terfenadine (Patent No Supply), Terfex, Terfinax, Ternadin, Triludan, dl-Terfenadine, α-(p-tert-Butylphenyl)-4-(α-hydroxy-α-phenylbenzyl)-1-piperidinebutanol

Description

Applications Nonsedating-type histamine H1-receptor antagonist. Antihistaminic.
References Carr, A.A., et al.: Arzneim. Forsch., 32, 1157 (1982), Badwan, A.A., et al.: Anal. Profiles Drug Subs., 19, 627 (1990), Masheter, H.C., et al.: Clin. Rev. Allergy, 11, 5 (1993), Jurima-Romet, M., et al.: Drug Metab. Dispos., 22, 849 (1994),

• Brand: TRC

Chemical properties

• Molecular weight: 471.67
• Formula: C₃₂H₄₁NO₂
• Color/Form: White To Off-White
• InChI: InChI=1S/C32H41NO2/c1-31(2,3)26-18-16-25(17-19-26)30(34)15-10-22-33-23-20-29(21-24-33)32(35,27-11-6-4-7-12-27)28-13-8-5-9-14-28/h4-9,11-14,16-19,29-30,34-35H,10,15,20-24H2,1-3H3
• InChI key: InChIKey=GUGOEEXESWIERI-UHFFFAOYSA-N
• SMILES: CC(C)(C)c1ccc(C(O)CCCN2CCC(C(O)(c3ccccc3)c3ccccc3)CC2)cc1