D-Tetrahydropalmatine

CAS: 3520-14-7

Ref. TR-T294160

Product Information

• Name: D-Tetrahydropalmatine
• Synonyms: (13aR)-5,8,13,13a-Tetrahydro-2,3,9,10-tetramethoxy-6H-dibenzo[a,g]quinolizine, 2,3,9,10-Tetramethoxy-13abeta-berbine, (+)-(R)-Tetrahydropalmatine, (+)-2,3,9,10-Tetramethoxyberbine, (+)-Corydalis B, (R)-Tetrahydropalmatine, (+)-Tetrahydropalmatine Alkaloid, Corydalis B

Description

Applications D-Tetrahydropalmatine is an alkaloid isolated from a traditional Chinese herb Rhizoma Corydalis (yanhusuo). D-Tetrahydropalmatine inhibits dopamine and serotonin uptake of synaptosomes in the rat brain. D-Tetrahydropalmatine also shows inhibitory effects on acetylcholinesterase and butyrylcholinesterase.
References Xu, S.X. et al.: Zhong. Yao Li Xue Bao, 8, 207 (1987); Chlebek, J. et al.: Nat. Prod. Comm., 6, 607 (2011); Hong, Z. et al.: Biopharm. Drug Dispos., 27, 111 (2006);

• Brand: TRC

Chemical properties

• Molecular weight: 355.43
• Formula: C₂₁H₂₅NO₄
• Color/Form: Light Yellow
• InChI: InChI=1S/C21H25NO4/c1-23-18-6-5-13-9-17-15-11-20(25-3)19(24-2)10-14(15)7-8-22(17)12-16(13)21(18)26-4/h5-6,10-11,17H,7-9,12H2,1-4H3/t17-/m1/s1
• InChI key: InChIKey=AEQDJSLRWYMAQI-QGZVFWFLSA-N
• SMILES: COc1cc2c(cc1OC)[C@H]1Cc3ccc(OC)c(OC)c3CN1CC2