Trichlormethiazide

CAS: 133-67-5

Ref. TR-T774335

Product Information

• Name: Trichlormethiazide
• Synonyms: 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3-(dichloromethyl)-3,4-dihydro-, 1,1-dioxide, 3-Dichloromethyl-6-chloro-7-sulfamoyl-3,4-dihydro-1,2,4-benzothiadiazine-1,1-dioxide, 3-Dichloromethyl-6-chloro-7-sulfamyl-3,4-dihydro-1,2,4-benzothiadiazine 1,1-dioxide, 3-Dichloromethylhydrochlorothiazide, 6-Chloro-3-(dichloromethyl)-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide, 6-Chloro-3-(dichloromethyl)-3,4-dihydro-7-sulfamyl-1,2,4-benzothiadiazine-1,1-dioxide, 6-Chloro-3-dichloromethyl-3,4-dihydro-7-sulfamoyl-2H-1,2,4-benzothiadiazine 1,1-dioxide, Achletin, Anatran, Anistadin, Aponorin, Carvacron, Ciba 7057-Su, Diurazida, Diurese, Diuroral, Esmarin, Fluitran, Flurese, Flutra, Gangesol, Hydrotrichlorothiazide, Intromene, Kubacron, Metahydrin, Metatensin, NSC 61560, Nakva, Naqua, Naquasone, Naquival, Salirom, Tachionin, Tolcasone, Trichlormetazid, Trichlormethiazid, Trichloromethiazide
• Brand: TRC
• Description: Applications Trichlormethiazide, is a diuretic, having similar properties as Hydrochlorothiazide (H714560). It is used for the treatment of oedema (including that which is associated with heart failure, hepatic cirrhosis and corticosteroid therapy) and hypertension.References Imamura, T., et al.: International Heart J., 54(1), 48 (2013); Takahashi, Y., et al.: Cardiovas. Diabetology, 10(1), 45 (2011)

Chemical properties

• Molecular weight: 380.66
• Formula: C₈H₈Cl₃N₃O₄S₂
• Color/Form: Neat
• InChI: InChI=1S/C8H8Cl3N3O4S2/c9-3-1-4-6(2-5(3)19(12,15)16)20(17,18)14-8(13-4)7(10)11/h1-2,7-8,13-14H,(H2,12,15,16)
• InChI key: InChIKey=LMJSLTNSBFUCMU-UHFFFAOYSA-N
• SMILES: NS(=O)(=O)c1cc2c(cc1Cl)NC(C(Cl)Cl)NS2(=O)=O