2,2,2-Trifluoroethanol

CAS: 75-89-8

Ref. TR-T790175

Product Information

• Name: 2,2,2-Trifluoroethanol
• Synonyms: 2,2,2-Trifluoroethyl alcohol, NSC 451, TFE, β,β,β-Trifluoroethyl alcohol, 1,1,2-Trifluoroethanol, 2,2,2-Trifluoraethanol, 2,2,2-Trifluorethanol, 2,2,2-Trifluoroetanol, 2,2,2-Trifluoroethan-1-ol, Chloro(Difluoro)Acetic Acid, Ethanol, 2,2,2-trifluoro-, Nsc 451, Trifluoroethanol, Trifluroroethyl alchohol
• CAS: 75-89-8

Description

Applications 2,2,2-Trifluoroethanol is used in the synthesis of competitive inhibitors for phospholipase A2. Used in the preparation of a key Efavirenz (E425000) intermediate, a nonnucleoside HIV-1 reverse transcriptase inhibitor. Antiviral.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Jain, M. et al.: Biochem., 30, 10256 (1991); Young, S.D., et al.: Antimicrob. Ag. Chemother., 39, 2602 (1995), Tan, L. et al.: Angew. Chem. Int. Ed., 38, 711 (1999);

• Brand: TRC

Chemical properties

• Molecular weight: 100.04
• Formula: C₂H₃F₃O
• Color/Form: Neat
• InChI: InChI=1S/C2H3F3O/c3-2(4,5)1-6/h6H,1H2
• InChI key: InChIKey=RHQDFWAXVIIEBN-UHFFFAOYSA-N
• SMILES: OCC(F)(F)F