Estimated delivery in United States, on Tuesday 28 May 2024
Product Information
Name:
Vismodegib
Controlled Product
Synonyms:
- Benzamide
- 2-chloro-N-[4-chloro-3-(2-pyridinyl)phenyl]-4-(methylsulfonyl)-
- 2-Chloro-N-[4-chloro-3-(2-pyridinyl)phenyl]-4-(methylsulfonyl)benzamide
- Erivedge
- GDC 0449
- Benzamide, 2-Chloro-N-[4-Chloro-3-(2-Pyridinyl)Phenyl]-4-(Methylsulfonyl)-
- Gdc-0449
- Vismodegib (GDC-0449)
CAS:
Description:
Applications Vismodegib targets the Hedgehog (Hh) pathway. Inhibition of the Hh signaling may be effective in the treatment and prevention of many types of human cancers. Potent Hedgehog inhibitor.
References Gupta, S. et al.: Ther. Advances in Med. Oncology 2,237(2010)
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
421.30
Formula:
C19H14Cl2N2O3S
Color/Form:
Off-White
InChI:
InChI=1S/C19H14Cl2N2O3S/c1-27(25,26)13-6-7-14(17(21)11-13)19(24)23-12-5-8-16(20)15(10-12)18-4-2-3-9-22-18/h2-11H,1H3,(H,23,24)
InChI key:
InChIKey=BPQMGSKTAYIVFO-UHFFFAOYSA-N
SMILES:
CS(=O)(=O)c1ccc(C(=O)Nc2ccc(Cl)c(-c3ccccn3)c2)c(Cl)c1
MDL:
Melting point:
Boiling point:
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Density:
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EINECS:
Merck:
HS code:
Technical inquiry about: TR-V674700 Vismodegib
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